RecruitingNot ApplicableNCT05085860

Acute Responses to Exercise in Females and Males With Symptomatic Atrial Fibrillation

Feasibility of Examining Acute Responses to Exercise in Symptomatic Females and Males With Atrial Fibrillation: a Pilot Randomized Crossover Study


Sponsor

Ottawa Heart Institute Research Corporation

Enrollment

36 participants

Start Date

Feb 8, 2022

Study Type

INTERVENTIONAL

Conditions

Summary

The main purpose of this pilot project is to measure the feasibility of conducting a randomized crossover study examining short-term changes in atrial fibrillation (AF) symptoms in symptomatic females and males with paroxysmal or persistent AF when they engage in a standard week of exercise (i.e. moderate-intensity continuous training \[MICT\] or high-intensity interval training \[HIIT\]) compared to a control week (i.e. no moderate to vigorous exercise over 7 days).


Eligibility

Min Age: 40 Years

Inclusion Criteria8

  • Paroxysmal and Persistent AF
  • Rate controlled (resting ventricular rate \<110 bpm)
  • Able to do a symptom limited exercise test
  • At least 40 years of age
  • Self-reports being symptomatic in the past 4 weeks
  • If female, self-reports being post-menopausal
  • Able to read and understand English or French
  • Agrees to sign informed consent

Exclusion Criteria6

  • Currently participating in routine exercise training
  • Unstable angina or uncontrolled diabetes mellitus; or established diagnosis of severe mitral or aortic stenosis, or hypertrophic obstructive cardiomyopathy with significant obstruction
  • Unable to access the Internet or a phone (iPhone and iPad require iOS version 10.0 and up, Android requires version 6.0 and up) during the study period
  • Has an automated external defibrillator, an implantable cardioverter defibrillator or other types of pacemaker
  • Unwilling or unable to complete the three conditions
  • Unable to provide written, informed consent

Interventions

BEHAVIORALModerate-intensity continuous training (MICT)

Participants will engage in exercise and record AF symptoms prospectively over 7 days

BEHAVIORALHigh-intensity interval training (HIIT)

Participants will engage in exercise and record AF symptoms prospectively over 7 days


Locations(1)

University of Ottawa Heart Institute

Ottawa, Ontario, Canada

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NCT05085860


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