Utility of 18FDOPA PET/MRI for Focal Hyperinsulinism

This study is using a specialized imaging test (called 18F-DOPA PET/MRI) to identify the exact location of abnormal insulin-producing cells in patients with a condition called focal hyperinsulinism — where a small cluster of cells in the pancreas produces too much insulin, causing dangerous low blood sugar episodes. **You may be eligible if...** - You have been diagnosed with hyperinsulinemic hypoglycemia (your pancreas makes too much insulin, causing low blood sugar) - You have not responded to medications like diazoxide or octreotide - Your doctor recommends surgery to prevent further dangerous low blood sugar episodes - You or your parent or guardian can provide signed consent **You may NOT be eligible if...** - You have a major illness that would make participation risky - You have a contraindication to MRI (like a pacemaker or metal implants) — though in that case a PET/CT may still be possible - Your family or guardians will not consider surgery as a treatment option Talk to your doctor to see if this trial is right for you.