RecruitingNot ApplicableNCT05543083

Cognitive-Behavioral Therapy and Exercise Training in Adolescents At-Risk for Type 2 Diabetes


Sponsor

Colorado State University

Enrollment

300 participants

Start Date

Jun 2, 2023

Study Type

INTERVENTIONAL

Conditions

Summary

The investigators are doing this study to learn more about how to prevent type 2 diabetes in teenage girls. The purpose of this study is to find out if taking part in a cognitive-behavioral therapy group, exercise training group, or a combination of cognitive-behavioral therapy and exercise training groups, decreases stress, improves mood, increases physical activity and physical fitness, and decreases insulin resistance among teenagers at risk for diabetes.


Eligibility

Sex: FEMALEMin Age: 12 YearsMax Age: 17 Years

Inclusion Criteria5

  • Female
  • Age 12-17 years
  • Body Mass Index (BMI)\>= 85 for age and sex
  • Type 2 Diabetes (T2D) first-or second-degree relative
  • Center for Epidemiologic Studies Depression Scale (CES-D) total score \>=21

Exclusion Criteria5

  • T2D/ Type 1 Diabetes (T1D) or any major medical condition (e.g. cardiovascular, renal) that would prohibit the ability to participate in exercise training
  • Diagnostic and Statistical Manual of Mental Disorders, 5th Edition (DSM-5) conduct disorder, substance abuse/ dependence, obsessive compulsive disorder, panic attacks, post-traumatic stress disorder, anorexia/bulimia, \& schizophrenia
  • Insulin sensitizers, weight loss medications \& chronic steroids
  • Structured weight loss treatment or bariatric surgery
  • Pregnancy, nursing

Interventions

BEHAVIORALCognitive-Behavioral Therapy followed by Exercise Training

6-week group CBT (cognitive-behavioral therapy; 1 hour/week for 6 weeks) followed by 6-week group exercise training (1 hour/week for 6 weeks). Home practice is assigned throughout the 12-week intervention period.

BEHAVIORALExercise Training followed by Cognitive-Behavioral Therapy

6-week group exercise training (1 hour/week for 6 weeks) followed by 6-week group CBT (1 hour/week for 6 weeks). Home practice is assigned throughout the 12-week intervention period.

BEHAVIORALCognitive-Behavioral Therapy Only

6-week group CBT (1 hour/week for 6 weeks), with continuation of group CBT for a second 6-week period (1 hour/week for 6 weeks). Home practice is assigned throughout the 12-week intervention period.

BEHAVIORALExercise Training Only

6-week group exercise training (1 hour/week for 6 weeks), with continuation of group exercise for a second 6-week period (1 hour/week for 6 weeks). Home practice is assigned throughout the 12-week intervention period.


Locations(2)

Children's Hospital Colorado

Aurora, Colorado, United States

Colorado State University

Fort Collins, Colorado, United States

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NCT05543083


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