RecruitingPhase 2NCT05102396

Topical Oxybutynin for Treatment of Hyperidrosis: Local or Systemic Effect?

Topical Oxybutynin Deodorant for Axillary Hyperhidrosis: Local or Systemic Effect? The TODAY Trial


Sponsor

Samantha Rodrigues Camargo Neves de Moura

Enrollment

17 participants

Start Date

Sep 26, 2022

Study Type

INTERVENTIONAL

Conditions

Summary

The TODAY trial is a study to evaluate the efficacy and safety of topical oxybutynin deodorant for use in patients with axillary hyperhidrosis.


Eligibility

Min Age: 18 YearsMax Age: 45 Years

Inclusion Criteria2

  • Patients aged ≥18 years and ≤ 45 years
  • Not treated patient with another drug or treatment methodology for the disease for at least 30 days

Exclusion Criteria6

  • Patients who are hypersensitive to oxybutynin hydrochloride.
  • Not treated patient with another drug or treatment methodology for the disease for at least 30 days
  • Patients who have menopausal symptoms
  • Patients who show signs of skin lesions in the armpit
  • Pregnancy. Women with the potential to bear children should be under contraceptive strategies and take a negative pregnancy test to be enrolled
  • Patients with COVID in the contagious phase (PCR+)

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Interventions

DRUGTopical oxybutynin spray

Participants will receive topical oxybutynin spray (10%).

DRUGTopical placebo spray

Participants will receive topical placebo spray.

DRUGOral oxybutynin

Participants will receive oxybutynin (tablets).


Locations(1)

Irmandade da Santa Casa de Misericórdia de São Paulo

São Paulo, São Paulo, Brazil

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NCT05102396


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