Reducing Dietary Acid With Food Versus Oral Alkali in People With Chronic Kidney Disease (ReDACKD)

This trial (ReDACKD) is comparing two ways to reduce acid load in the body in people with chronic kidney disease (CKD): changing to a more plant-based, low-acid diet versus taking oral baking soda-like supplements (alkali pills). When the kidneys are weakened, they struggle to remove acid from the blood, which speeds up kidney decline. This study explores whether food changes or supplements work better. **You may be eligible if...** - You are 18 or older with a kidney filtration rate (eGFR) between 15 and 40 (moderate to severe CKD) - You have two recent blood tests showing low bicarbonate (a sign of acid buildup) - Your blood pressure is controlled below 160/100 mmHg - Your potassium level is below 5.3 - You are a patient at a nephrology clinic in Winnipeg or Halifax - You can communicate in English **You may NOT be eligible if...** - You are on dialysis or had acute kidney injury in the past 3 months - You have severe COPD requiring oxygen, class 3–4 heart failure, or had a heart attack or stroke in the past 6 months - You are currently on potassium-binding therapy - You are pregnant or breastfeeding - You have participated in another drug trial in the past 12 weeks Talk to your doctor to see if this trial is right for you.