RecruitingNCT05117723

Intraductal Papillary Mucinous Neoplasm (IPMN) Database - A Tool to Predict Pancreatic Cancer

Sponsor

St Vincent's Hospital Melbourne

Enrollment

1,000 participants

Start Date

Aug 26, 2021

Study Type

OBSERVATIONAL

Conditions

IPMN, Pancreatic IPMN

Summary

Pancreatic cancer is the 5th leading cause of cancer death in Australia. Surgery remains the most effective treatment for early pancreatic cancer and currently the only potential for cure. Unfortunately, many patients present with advanced disease and are not suitable for surgery. Therefore, it is vital to detect these cancers early. In the absence of significant data from prospective studies, all of the guidelines are based on a critical review of available data and consensus of experts. The primary aim is to delineate the progression of IPMN to pancreatic malignancy as confirmed by surgical pathology, radiology and biochemical diagnosis. The secondary aims are (i) To outline the management of IPMNs for those who have progressed straight to surgery or surveillance by endoscopic ultrasound (EUS) (ii)To validate the International consensus guidelines for management of IPMN - Fukuoka consensus guidelines and tertiary aim to identify potential risk factors, if any that increase risk of malignancy within the IPMNs.

Eligibility

Min Age: 18 YearsMax Age: 90 Years

Plain Language Summary

Simplified for easier understanding

This is a database registry study — not a treatment trial — for people found to have an intraductal papillary mucinous neoplasm (IPMN) on imaging. An IPMN is a cyst (fluid-filled sac) that grows inside the ducts of the pancreas. While most IPMNs are harmless, some can slowly develop into pancreatic cancer over time. This registry collects clinical information and imaging findings from patients over many years to help researchers build a tool that can better predict which cysts are most likely to become cancerous — so doctors can know when to watch and wait versus when to operate. **You may be eligible if...** - You are an adult aged 18 to 90 years old - Imaging (such as CT, MRI, or ultrasound) has found a cystic (fluid-filled) mass in your pancreas that is consistent with an IPMN **You may NOT be eligible if...** - You formally decline to be enrolled in the registry This is an observational study — there is no experimental treatment involved. Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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