RecruitingNot ApplicableNCT05120492

Optimal Management of Extreme Obesity and Severe Knee Osteoarthritis Feasibility Trial


Sponsor

Nova Scotia Health Authority

Enrollment

20 participants

Start Date

Apr 22, 2022

Study Type

INTERVENTIONAL

Conditions

Summary

Does weight loss surgery in patients with morbid obesity prior to knee replacement surgery improve outcomes from knee replacement surgery


Eligibility

Min Age: 18 YearsMax Age: 65 Years

Inclusion Criteria1

  • severe knee osteoarthritis body-mass index of 45 to 60

Exclusion Criteria1

  • previous total replacement of the same knee, a need for bilateral total knee replacement, and knee pain during the previous week that the patient rated at higher than 60 mm on a 100-mm visual-analogue scale. Also,prior bariatric or complex foregut surgery, significant cardiovascular, pulmonary, renal, liver, gastrointestinal, psychiatric disorders, pregnancy, malignancy within last 5 years, anemia, coagulopathy requiring anti-coagulation therapy.

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Interventions

PROCEDUREbariatric surgery followed by total knee replacement

The only intervention is the randomization of the priority of the 2 procedures.


Locations(1)

Nova Scotia Health

Halifax, Nova Scotia, Canada

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NCT05120492


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