Treatment for Sacroiliac Joint Pain Using Platelet-rich Plasma (PRP) Versus Steroid/Anesthetic

This study compares two treatments for sacroiliac joint (SIJ) pain — platelet-rich plasma (PRP) injections versus the standard steroid and anesthetic injection. The sacroiliac joint connects the lower spine to the pelvis, and pain in this area can be debilitating. PRP uses your own blood platelets to potentially promote healing, and researchers want to know if it works better than steroids. You may be eligible if... - You are over 18 years old - You have been diagnosed with sacroiliac joint pain by a physiatrist or pain specialist - Your pain was confirmed by a diagnostic anesthetic block (50% or greater pain reduction) - Your pain is at least 4/10 and has lasted at least 6 weeks You may NOT be eligible if... - You have had a steroid injection to the sacroiliac joint in the past 6 months - You are currently on antibiotic therapy for an active infection - You are on systemic immunosuppressants - You are pregnant Talk to your doctor to see if this trial is right for you.