RecruitingNot ApplicableNCT05121961

Treatment for Sacroiliac Joint Pain Using Platelet-rich Plasma (PRP) Versus Steroid/Anesthetic

Treatment for Sacroiliac Joint Pain Using Platelet-rich Plasma (PRP) Regenerative Therapy: A Randomized Controlled Trial in Comparison With Steroid/Anesthetic Injection With Advanced MR Analysis


Sponsor

University of Utah

Enrollment

50 participants

Start Date

Feb 22, 2020

Study Type

INTERVENTIONAL

Conditions

Summary

The purpose of this study is to determine if platelet-rich plasma is superior to steroid/anesthetic for the treatment of sacroiliac joint pain.


Eligibility

Min Age: 18 Years

Inclusion Criteria3

  • Adult (\>18 y/o) males and females referred for therapeutic injection to the investigators spine interventional service by a physiatrist or pain anesthesiologist with a clinical diagnosis of SIJ pain confirmed by history
  • % or greater reduction in pain by a diagnostic anesthetic block using no more than 1.5 cc 2% lidocaine performed under imaging guidance by a pain interventionalist (PM\&R, Pain Anesthesia, or Neuroradiology Spine Intervention).
  • Baseline pain must be \>/=4 by numeric rating scale (NRS), at least 6 weeks in chronicity, and must not be multi-factorial (related to radiculopathy or axial pain localizing elsewhere) by physical examination or confounding medical history (infection, inflammatory spondyloarthropathy, or osseous metastatic disease).

Exclusion Criteria4

  • SIJ steroid treatment within the prior 6 months.
  • Patients with a history of infection currently on antibiotic therapy
  • Usage of systemic immunosuppressants
  • Pregnancy

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Interventions

PROCEDURESacroiliac intra-articular injection

CT guided injection of platelet-rich plasma versus steroid/anesthetic into the sacroiliac joint


Locations(2)

University of Utah

Salt Lake City, Utah, United States

Veterans Administration Salt Lake City Health Care System

Salt Lake City, Utah, United States

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NCT05121961


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