RecruitingNot ApplicableNCT05122897

Investigation of Biofilm Formation on Temporary push-on Rings of Implant Crowns

Temporary push-on Rings of Antimicrobial Alloys for Transmucosal Implant Abutment Systems: a Randomized Clinical Study on Early and Mature Biofilm Formation

Sponsor

University Hospital, Basel, Switzerland

Enrollment

33 participants

Start Date

Jan 11, 2022

Study Type

INTERVENTIONAL

Conditions

Peri-implantitis Oral Biofilm Dental Plaque

Summary

This in-vivo study investigates early (48h), mature (2 weeks) and long-term (3 months) biofilm formation and composition on temporary push-on cones (exchangeable conical rings) made of noble-alloy-based materials (Pagalinor, PA) in comparison to Titanium-6Aluminum-7Niobium alloy (TAN) presently used in the transmucosal portion of dental implant abutments.

Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study examines how bacteria (biofilm) accumulate on temporary push-on rings used in dental implant crowns. Understanding this helps improve dental implant hygiene and design. Participants who have at least one dental implant will have the temporary ring analyzed for bacterial buildup over a short study period. You may be eligible if... - You are 18 years or older - You have one or more bone-level titanium dental implants awaiting a final crown - You do not have active gum disease (probing pocket depth 4mm or less) - You do not smoke heavily (fewer than 10 cigarettes per day) - You are not on any pharmacological treatment or antibiotics in the past 3 months You may NOT be eligible if... - You have a systemic illness such as diabetes - You smoke more than 10 cigarettes per day - You have active gum disease (probing pocket depth more than 4mm) - You are pregnant - You have used antibiotics or prescription medications in the past 3 months Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DEVICERings made of PA (test)

Rings made of PA (test) 0.2mm in thickness are pushed on the conical titanium base (abutment) of implant crowns and are removed and replaced after 48h, 2 weeks and 3 months for quantification of the bacterial biofilm. Test rings are applied in a split-mouth design provided that 2 implants are present (total of 4 months study period), or one after the other when only 1 implant is present (total of 8 months study period).

DEVICERings made of TAN (control)

Rings made of TAN (control) 0.2mm in thickness are pushed on the conical titanium base (abutment) of implant crowns and are removed and replaced after 48h, 2 weeks and 3 months for quantification of the bacterial biofilm. Control rings are applied in a split-mouth design provided that 2 implants are present (total of 4 months study period), or one after the other when only 1 implant is present (total of 8 months study period).