Can Overall Adenoma Detection Rate Replace Screening Adenoma Detection Rate ? Multicenter Study
Improving Colonoscopy Adenoma Detection Metrics by Extending the Screening-only Measurement to All Indications: a Prospective Multicenter Study
Evergreen General Hospital, Taiwan
2,700 participants
Nov 20, 2021
OBSERVATIONAL
Conditions
Summary
This is a prospective equivalence colonoscopy study evaluating whether overall adenoma detection rate (ADR) is a reliable alternate for screening ADR. Overall indication includes screening, surveillance, and diagnostic indications.
Eligibility
Inclusion Criteria1
- consecutive patients aged ≥50 years undergoing colonoscopy are eligible for enrollment.
Exclusion Criteria11
- high risk family history of colorectal cancer (CRC) e.g., familial adenomatous polyposis, hereditary non-polyposis CRC syndrome, multiple first degree relatives with CRC, or a single first degree relative with CRC at <60 years
- serrated polyposis syndrome
- inflammatory bowel disease
- colonoscopy to remove a large neoplastic polyps
- obstructive lesions of the colon
- gastrointestinal bleeding
- current participation in other studies
- hospitalized patients
- mental retardation
- pregnancy
- refusal to provide a written informed consent.
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Interventions
The investigators will compare ADRs using traditional screening-restricted definition and combined screening, surveillance, and diagnostic indication (i.e., overall-non-FIT indication). The impact of addition of FIT+ indication into the overall indication (i.e., overall-FIT indication) on ADR will also be evaluated.
Locations(6)
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NCT05125939