Immune Score Based Radiomics in Nasopharyngeal Carcinoma

This study is developing an imaging-based tool (called radiomics) to estimate the immune status of nasopharyngeal carcinoma — a type of head and neck cancer arising at the back of the nose — without needing a biopsy. By analyzing patterns in routine MRI scans combined with immune biomarker testing, researchers hope to predict how tumors respond to treatment and personalize therapy decisions. **You may be eligible if...** - You have a new, biopsy-confirmed diagnosis of nasopharyngeal carcinoma (non-keratinizing or keratinizing) - Your ECOG performance status is 0–1 (fully active or with minor activity restriction) - Your liver, kidney, and blood counts are within normal limits - You have given written informed consent **You may NOT be eligible if...** - You have a contraindication to MRI scanning - You have had a prior cancer (other than skin basal/squamous cell carcinoma) - You have previously received chemotherapy or radiation - You are pregnant or breastfeeding - You have uncontrolled serious illness (unstable heart disease, poorly controlled diabetes, severe liver or kidney disease) Talk to your doctor to see if this trial is right for you.