RecruitingNot ApplicableNCT05127616

EPPIC: Easing Pelvic Pain Interventions Clinical Research Program

A Brief, Transdiagnostic Cognitive Behavioral Treatment for Urological Chronic Pelvic Pain Syndrome: Processes, Predictions, Outcomes

Sponsor

State University of New York at Buffalo

Enrollment

240 participants

Start Date

Aug 10, 2022

Study Type

INTERVENTIONAL

Conditions

Chronic Pain Chronic Pelvic Pain Syndrome Chronic Prostatitis Interstitial Cystitis Bladder Pain Syndrome Urologic Chronic Pelvic Pain Syndrome (UCPPS)Chronic Overlapping Pain Disorders

Summary

The EPPIC (Easing Pelvic Pain Interventions Clinical Research Program) study evaluates an ultra-brief, 4 session cognitive behavioral pain treatment transdiagnostic in design for urologic chronic pain syndrome (UCPPS) with clinical and practical advantages over existing behavioral therapies whose length and focus limits their adoption by clinicians and coverage for mechanistically similar comorbidities. A theoretically informed, practical, empirically grounded approach will systematically unpack CBT's working mechanisms, clarify for whom it works, ease dissemination, appeal to patients, providers, payers, and policy makers in the COVID-19 era favoring low resource intensity treatments, and reduce cost and inefficiencies associated with high intensity therapies whose complexity, length, and scarcity restricts uptake and impact.

Eligibility

Min Age: 18 YearsMax Age: 70 Years

Plain Language Summary

Simplified for easier understanding

This study tests two non-drug treatments — Cognitive Behavioral Therapy (CBT) versus a Support and Education program — for people with interstitial cystitis/bladder pain syndrome (IC/BPS) or chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS). These are chronic pelvic pain conditions with few effective treatments. The study aims to reduce pain and improve quality of life using psychological tools. You may be eligible if... - You are between 18 and 70 years old - You have a confirmed diagnosis of IC/BPS or CP/CPPS by a urologist or urogynecologist - You have had pelvic pain or discomfort for at least 6 months - Your pain is at least 3 out of 10 and affects your daily activities or quality of life - You have at least a 6th-grade reading level and can commit to attending sessions and completing diaries You may NOT be eligible if... - You have a neurological condition affecting the bladder (e.g., multiple sclerosis, Parkinson's) - You have been diagnosed or treated for a pelvic cancer - You have a major psychiatric disorder, active substance abuse, or schizophrenia - You are currently in psychotherapy for urological symptoms - You cannot speak or read English Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

BEHAVIORALMinimal Contact-Cognitive Behavior Therapy

This 4 session largely home-based version of CBT with minimal therapist contact treatment is aimed at improving UCPPS symptoms by teaching symptom self-management skills that modify illness beliefs, information processing strategies, and reactions that aggravate pelvic pain and urinary symptoms.

BEHAVIORALPatient Education/Support

This 4 session largely home-based treatment is aimed at improving UCPPS symptoms through the provision of support and science-based information about UCPPS symptoms, how it is diagnosed, its causes, impacts, and triggers, treatment options and a collaborative relationship between the patient and clinician.