Supporting Treatment Access and Recovery in COD
Supporting Treatment Access and Recovery in Co-Occurring Opioid Use and Mental Health Disorders
University of Massachusetts, Worcester
1,000 participants
Mar 11, 2022
INTERVENTIONAL
Conditions
Summary
This 4-year study will randomize 1,000 people with co-occurring opioid use and mental health disorders (COD) at medication for opioid use disorder (MOUD) clinics to evaluate the effectiveness of MISSION, a multi-component team approach, or its components with MOUD versus MOUD alone, as well as the incremental benefits of MISSION or its components for improving outcomes. We expect that individuals receiving MISSION or its parts + MOUD will show greater improvement over MOUD alone on: engagement, substance use, and mental health.
Eligibility
Inclusion Criteria5
- Are 18 years-old and older;
- Are fluent in English or Spanish;
- Have OUD who (a) are newly admitted into the program with OUD; or (b) who have been active in the program for the treatment of OUD with medications like buprenorphine or naltrexone, but experienced a recent relapse with any substance (e.g., alcohol, cocaine, opioids, or benzodiazepines). This second group is necessary to include because patients who may have been stable for a long period of time may have a relapse and need intensive treatment to help them regain their abstinence and facilitate the path towards recovery. Thus, by taking those newly enrolled and those who were stable on MOUD but had a recent relapse, the second group is clinically similar to the first group and the intervention will be meaningful.;
- Able to provide consent;
- Potentially have a concurrent substance use disorder in addition to opioids; and
Exclusion Criteria4
- Are not fluent in English or Spanish;
- Are acutely psychotic, acutely suicidal with a plan, or homicidal;
- Are incompetent and unable to provide informed consent; and
- Have concurrent severe alcohol use disorder or high dose benzodiazepine needing detoxification. This exclusion factor is based on DSM-5 criteria, and those who are currently drinking or with a history of severe alcohol withdrawal (i.e., alcohol related seizures, and delirium tremens) will also be excluded. High dose benzodiazepine is defined as using Lorazepam equivalent of > 10 mg/day; Diazepam > 100 mg/day; Clonazepam 5 mg/ day; Alprazolam 5 mg/day.
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Interventions
medication management
offering intensive community-based services that decrease in intensity over time
including 11 recovery-oriented sessions from someone with lived experience of co-occurring disorders
comprised of 13 structured co-occurring disorders treatment sessions
Locations(5)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT05138614