Effects of Combination Medical Therapy Followed by BPA on Right Ventricular-PA Coupling and Hemodynamics in CTEPH

This study looks at how starting drug therapy followed by a minimally invasive lung procedure (balloon pulmonary angioplasty/BPA) affects heart function in people with chronic thromboembolic pulmonary hypertension (CTEPH) — a type of high blood pressure in the lungs caused by old blood clots. **You may be eligible if...** - You are 18 or older - You have been diagnosed with CTEPH - You are not a candidate for surgical clot removal (pulmonary thromboendarterectomy) - You are suitable for balloon pulmonary angioplasty (BPA) - You have not yet started any CTEPH/PAH-specific medication **You may NOT be eligible if...** - You are already on CTEPH or pulmonary hypertension medications - You are a candidate for surgical removal of the clots - You are not suitable for BPA based on anatomy Talk to your doctor to see if this trial is right for you.