RecruitingNot ApplicableNCT05146180
Interest of Parametric Positron Emission Imaging in the Diagnosis of Infections on Cardiac Valve Prosthesis
Interest of Parametric Positron Emission Computed Tomography Imaging in the Diagnosis of Infections on Cardiac Valve Prosthesis : PARAVA Study
Sponsor
Centre Henri Becquerel
Enrollment
30 participants
Start Date
Feb 24, 2022
Study Type
INTERVENTIONAL
Conditions
Summary
The objective of this study is to determine if early parametric positron emission computed tomography is useful to diagnose cardiac prosthetic valve infections.
Eligibility
Min Age: 18 Years
Inclusion Criteria8
- Age superior to18 years,
- Effective contraception for women of childbearing age or negative pregnancy test on the day of the exam
- Good general condition. WHO ≤ 1
- Suspicion of endocarditis on a prosthetic heart valve implanted more than 3 months ago
- Labeled polynuclear scintigraphy performed within a maximum of 15 days before positron emission computed tomography
- Standard positron emission computed tomography planned as part of the extension assessment
- Informed and signed consent before any specific study procedure.
- Patient affiliated to the social security system
Exclusion Criteria6
- Presence of an active cancer in the previous three years
- Pregnancy or breastfeeding
- Poorly controlled diabetic patients
- Protected adults (under guardians or curators)
- Impossible decubitus (orthopnea, ...),
- Hypersensitivity to FDG or to one of the excipients of the radiopharmaceutical.
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Interventions
DEVICEParametric positron emission computed tomography
Patients will undergo parametric positron emission computed tomography in 15 days after the labeled polynuclear scintigraphy
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT05146180
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