Endocarditis Clinical Trials

10 recruiting

Frequently Asked Questions

Common questions about Endocarditis clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 32 trials

Recruiting
Phase 3

Bacteriophages in Addition to Antibiotics for the Treatment of Patients With Infective Endocarditis

Endocarditis, Bacterial
University Clinical Hospital na V.V.Vinogradov (branch of RUDN university na Patrice Lumumba)30 enrolled1 locationNCT06870409
Recruiting
Phase 4

Clopidogrel vs. Aspirin for Cardiovascular Risk Reduction in Patients With S. Aureus Bacteremia

Staphylococcus Aureus EndocarditisStaphylococcus Aureus SepticemiaStaphylococcus Aureus Bloodstream Infection
Todd C. Lee MD MPH FIDSA300 enrolled1 locationNCT06650488
Recruiting
Phase 4

Dabigatran vs. Oral Anti-Xa Inhibitors in S. Aureus Bacteremia

Staphylococcus Aureus BacteremiaStaphylococcus Aureus EndocarditisStaphylococcus Aureus Septicemia+3 more
McGill University Health Centre/Research Institute of the McGill University Health Centre300 enrolled1 locationNCT06650501
Recruiting
Phase 4

Daptomycin vs. Vancomycin for the Treatment of Methicillin Resistant S. Aureus Bacteremia

Staphylococcus Aureus BacteremiaStaphylococcus Aureus EndocarditisStaphylococcus Aureus Septicemia+2 more
Todd C. Lee MD MPH FIDSA300 enrolled14 locationsNCT06637332
Recruiting
Phase 4

Oral Antimicrobial Treatment vs. Outpatient Parenteral for Infective Endocarditis

Endocarditis Infective
Fundacion Clinic per a la Recerca Biomédica360 enrolled20 locationsNCT05398679
Recruiting
Not Applicable

Healthrelated Quality of Life and Experiences of a Heart Rehabilitation Programme After Care for Infective Endocarditis.

Patient ParticipationBacterial InfectionsInfective Endocarditis+1 more
Region Halland50 enrolled1 locationNCT06704048
Recruiting
Phase 2

Combination Cefazolin With Ertapenem for Methicillin-susceptible Staphylococcus Aureus Bacteremia

Staphylococcus Aureus BacteremiaStaphylococcus Aureus EndocarditisStaphylococcus Aureus Septicemia+1 more
Todd C. Lee MD MPH FIDSA60 enrolled5 locationsNCT04886284
Recruiting
Phase 2

Contribution of PET/CT With Gallium 68 Citrate (68Ga-PET/CT) for the Diagnosis of Prosthetic Valve Infective Endocarditis

Infective Endocarditis
University Hospital, Bordeaux40 enrolled1 locationNCT05446376
Recruiting

San Matteo Endocarditis Registry STEADY

Endocarditis Infective
Fondazione IRCCS Policlinico San Matteo di Pavia418 enrolled1 locationNCT07346222
Recruiting
Not Applicable

Interest of Parametric Positron Emission Imaging in the Diagnosis of Infections on Cardiac Valve Prosthesis

Endocarditis
Centre Henri Becquerel30 enrolled1 locationNCT05146180
Recruiting

Betalactam Pharmacokinetics in Endocarditis Patients

Infective Endocarditis
Uppsala University150 enrolled4 locationsNCT04647331
Recruiting
Phase 3

Adjunctive Rifampin for the Treatment of Prosthetic Valve Endocarditis Due to S. Aureus

Prosthetic Valve EndocarditisStaphylococcus Aureus Endocarditis
Todd C. Lee MD MPH FIDSA330 enrolled1 locationNCT07253688
Recruiting
Not Applicable

Echocardiography Versus no Echocardiography in S. Aureus Bacteraemia and VIRSTA Score < 3

Staphylococcus AureusBacteremiaInfective Endocarditis
Assistance Publique - Hôpitaux de Paris700 enrolled1 locationNCT06457386
Recruiting

Prospective Cohort Study of Patients With Infective Endocarditis at Pitié-Salpêtrière Hospital

Infective Endocarditis
Assistance Publique - Hôpitaux de Paris700 enrolled1 locationNCT04992923
Recruiting
Phase 3

New Treatment of Cardiac Device Infections; Immediate Reimplantation After Removal of Infected System

Endocarditis, Bacterial
Rigshospitalet, Denmark176 enrolled1 locationNCT06250985
Recruiting

French National Observatory on Infective Endocarditis

Infective Endocarditis
Central Hospital, Nancy, France5,000 enrolled1 locationNCT03272724
Recruiting
Not Applicable

CBCT vs OPT on the Oral Health Status at 12 Months of Patients Hospitalized for Infective Endocarditis.

Infective Endocarditis
Nantes University Hospital170 enrolled10 locationsNCT06269679
Recruiting
Not Applicable

Reducing Risk for Infective Endocarditis

BacteremiaInfective Endocarditis
Wake Forest University Health Sciences320 enrolled6 locationsNCT05721781
Recruiting

Impact of Preoperative Dental Screening in Reducing Infective Endocarditis Risk in Surgical Valve Replacement Patients

EndocarditisSurgical Valve ReplacementDental
Odense University Hospital1,000 enrolled1 locationNCT06403839
Recruiting
Not Applicable

Evolution of PET Fixation With FDG at the End of Antibiotic Treatment of Infective Endocarditis on Valvular Prosthesis

Prosthetic Valve Endocarditis
Assistance Publique - Hôpitaux de Paris50 enrolled1 locationNCT05989152