RecruitingNCT05147519

Protocol RV 583 Multinational Observational Cohort of HIV and Other Infections

Multinational Observational Cohort of HIV and Other Infections (MOCHI)


Sponsor

Henry M. Jackson Foundation for the Advancement of Military Medicine

Enrollment

2,500 participants

Start Date

Nov 5, 2021

Study Type

OBSERVATIONAL

Conditions

Summary

Multinational Observational Cohort of HIV and other Infections (MOCHI). This observational study is to gain information regarding the number of new HIV infections among people who engage in behaviors that make them vulnerable to acquiring HIV across multiple international sites.


Eligibility

Min Age: 14 YearsMax Age: 55 Years

Inclusion Criteria5

  • Considered to be vulnerable to HIV and other STIs based on any one or more of the following test results and/or self-reported behaviors:
  • Documented history of newly diagnosed syphilis, gonorrhea, chlamydia, Mycoplasma genitalium, herpes simplex virus, or acute hepatitis C virus infection in the 24 weeks prior to screening
  • Self-reported vaginal, oral, or anal intercourse in exchange for money as a regular source of income
  • Self-reported condomless vaginal or anal intercourse with at least three different partners living with HIV or of unknown status in the 24 weeks prior to screening
  • Self- reported injection drug use (IDU) in the 24 weeks prior to screening

Interventions

BEHAVIORALNovel interventions to achieve HIV remission

To establish a group of well-characterized people living with HIV who initiated ART during acute or early HIV transmission that can serve as a source population for future studies, including those designed to test novel interventions to achieve HIV remission.


Locations(3)

Kenya Medical Research Institute/ USAMRD-A/Kenya (Kericho)

Kericho, Kenya

Institute of Clinical Epidemiology, National Institutes of Health, University of the Philippines Manila

Manila, Philippines

Makerere University Walter Reed Program

Makerere, Kampala, Uganda

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NCT05147519


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