RecruitingPhase 1NCT05147675

Safety of Cultured Allogeneic Adult Umbilical Cord Derived Mesenchymal Stem Cells for OA

Safety of Cultured Allogeneic Adult Umbilical Cord Derived Mesenchymal Stem Cells for the Treatment of Osteoarthritis

Sponsor

The Foundation for Orthopaedics and Regenerative Medicine

Enrollment

92 participants

Start Date

Dec 1, 2022

Study Type

INTERVENTIONAL

Conditions

Osteoarthritis Spinal Arthritis

Summary

This trial will study the safety and efficacy of cultured allogeneic adult umbilical cord derived mesenchymal stem cells delivered intravenously and intraarticularly for the treatment of Osteoarthritis.

Eligibility

Inclusion Criteria2

Diagnosis of Osteoarthritis
Understanding and willingness to sign a written informed consent document

Exclusion Criteria10

Active infection
Active cancer
Chronic multisystem organ failure
Pregnancy
Clinically significant Abnormalities on pre-treatment laboratory evaluation
Medical condition that would (based on the opinion of the investigator) compromise patient's safety.
Continued drug abuse
Pre-menopausal women not using contraception
Previous organ transplant
Hypersensitivity to sulfur