RecruitingNot ApplicableNCT05163600

The Acute Cardiorespiratory Response to Blood-flow Restricted Versus Traditional Exercise Training Regimens (CaRe BFR)

The Acute Cardiorespiratory Response to Blood-flow Restricted Versus Traditional Exercise Training Regimens (CaRe BFR):4 Randomized Crossover Studies


Sponsor

University of Zurich

Enrollment

24 participants

Start Date

May 20, 2022

Study Type

INTERVENTIONAL

Conditions

Summary

The investigators hypothesize that BFR exercise regimens result in a different acute cardiorespiratory response pattern compared to traditional exercise regimens. Furthermore, the investigators hypothesize that these patterns differ between healthy participants and participants with COPD. Regarding secondary objective, the investigators hypothesize that BFR results in lower blood pressure responses compared to traditional exercise training in both healthy and COPD participants.


Eligibility

Min Age: 18 YearsMax Age: 90 Years

Inclusion Criteria5

  • Inclusion and exclusion for the healthy participants are defined by the following criteria.
  • Age ≥ 18 years
  • Clinically healthy
  • Age ≥ 18 years
  • Diagnosed COPD according to GOLD-guidelines12

Exclusion Criteria14

  • Physical or intellectual impairment precluding informed consent or protocol adherence
  • Non-German speaking (precluding informed consent)
  • Pain during exercise of any origin
  • Pregnancy
  • History of thromboembolic event in the lower extremity
  • Resting systolic blood pressure \<100 mmHg
  • Inclusion and exclusion for the COPD participants are defined by the following criteria.
  • Physical or intellectual impairment precluding informed consent or protocol adherence
  • Non-German speaking (precluding informed consent)
  • Acute or recent (within the last 6 weeks) exacerbation of COPD
  • Pain during exercise of any origin
  • Pregnancy
  • History of thromboembolic event in the lower extremity
  • Resting systolic blood pressure \<100 mmHg

Interventions

OTHERBlod flow restriction training

includes one strength and one endurance training


Locations(1)

University Hospital Zürich

Zurich, Switzerland

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NCT05163600


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