RecruitingNot ApplicableNCT05163600

The Acute Cardiorespiratory Response to Blood-flow Restricted Versus Traditional Exercise Training Regimens (CaRe BFR)

The Acute Cardiorespiratory Response to Blood-flow Restricted Versus Traditional Exercise Training Regimens (CaRe BFR):4 Randomized Crossover Studies


Sponsor

University of Zurich

Enrollment

24 participants

Start Date

May 20, 2022

Study Type

INTERVENTIONAL

Conditions

Summary

The investigators hypothesize that BFR exercise regimens result in a different acute cardiorespiratory response pattern compared to traditional exercise regimens. Furthermore, the investigators hypothesize that these patterns differ between healthy participants and participants with COPD. Regarding secondary objective, the investigators hypothesize that BFR results in lower blood pressure responses compared to traditional exercise training in both healthy and COPD participants.


Eligibility

Min Age: 18 YearsMax Age: 90 Years

Plain Language Summary

Simplified for easier understanding

This study is comparing blood-flow restriction (BFR) exercise — where a cuff is used to partially limit blood flow during low-intensity exercise — with traditional exercise, to understand how each affects the heart and lungs. The study includes both healthy people and those with COPD (chronic lung disease). **You may be eligible if...** - You are 18 years of age or older - You are either clinically healthy OR you have been diagnosed with COPD according to standard guidelines - You can speak and understand German (required for informed consent) **You may NOT be eligible if...** - You have a physical or intellectual impairment that prevents safe participation - You experience pain during exercise - You are pregnant - You have had a blood clot in your leg (deep vein thrombosis) - Your resting blood pressure is very low (below 100 mmHg systolic) - For COPD group: you have had a flare-up in the last 6 weeks Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

OTHERBlod flow restriction training

includes one strength and one endurance training


Locations(1)

University Hospital Zürich

Zurich, Switzerland

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NCT05163600


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