Evaluating Personalized Therapeutics Clinic (PTC) on Drug-Drug Interactions and Drug-Gene Interactions
Evaluating the Effectiveness of a Personalized Therapeutics Clinic (PTC) Intervention on Drug-Drug Interactions (DDIs) and Drug-Gene Interactions (DGIs)
University of Chicago
1,300 participants
Nov 30, 2022
INTERVENTIONAL
Conditions
Summary
The purpose of this study is to determine whether a consultation with a Personalized Therapeutics Clinic, or PTC, will help participants lower the risk for side effects (drug-drug interactions and drug-gene interactions) when taking many medications and help providers improve prescribing decisions for participants. A PTC is a clinical that will test your genes to gather information about your health that may help guide prescribing advice and offer you new information about your prescriptions. Doctors leading this study will look for variations (differences) in your genes that may suggest that you are at greater risk of having side effects or a greater chance of benefiting from certain medications. Individuals in this study will participate for roughly 9 months.
Eligibility
Inclusion Criteria3
- Adult participants cared for by a participating provider at University of Chicago Medical Center.
- Participants must be at least 18 years of age.
- Participants prescribed 5 or medication medications and taking a perpetrator drug or a drug with actionable pharmacogenomic information.
Exclusion Criteria5
- Participants who have undergone, or are being actively considered for, liver or kidney transplantation.
- Participation in another pharmacogenomic study.
- Participants who have previously received genotyping from another source.
- Inability to understand and give informed consent to participate.
- Inclusion of Women, Minorities, and Other Underrepresented Populations Individuals of all races and ethnic groups and genders are eligible for this trial.
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Interventions
A profile based on genetic testing that shows information about how the participant's medications they are taking interact with each other.
A profile based on genetic testing that shows information about how the participant's genes interact with/respond to certain medications they are taking.
The standard treatment and prescribing for the participant's specific type of cancer.
Locations(1)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT05166694