RecruitingNot ApplicableNCT05166850

Preventative Intervention for Cholera for 7 Days

Evidence Based Targeted Water Sanitation, and Hygiene Interventions to Reduce Cholera in Hotspots in the Democratic Republic of the Congo


Sponsor

Johns Hopkins Bloomberg School of Public Health

Enrollment

2,900 participants

Start Date

Dec 22, 2021

Study Type

INTERVENTIONAL

Conditions

Summary

The first objective of our study is to develop a theory-driven evidence-based targeted water, sanitation, and hygiene (WASH) intervention for household members of diarrhea patients in South Kivu, Democratic Republic of the Congo (DRC) through formative research and community engagement. The second objective is to conduct a randomized controlled trial of 2,320 household members of 580 severe diarrhea patients to evaluate the effectiveness of the developed targeted WASH intervention in terms of: 1. reducing diarrheal diseases household members of cholera and severe diarrhea patients; and 2. increasing WASH behaviors.


Eligibility

Inclusion Criteria5

  • Diarrhea patients presenting with three or more loose stools over a 24h period
  • Having no running water inside of their home
  • Plan to reside in Bukavu for the next 12 months
  • Have a child \<5 years in their household
  • Have a working mobile phone in the household

Exclusion Criteria2

  • No one will be excluded because of age, sex, religion, or sexual preference
  • Presenting at the health facility with a fever (COVID-19 prevention)

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Interventions

BEHAVIORALPICHA7 mHealth program

The PICHA7 mHealth program is first delivered during a health facility visit by a health promoter bedside to a diarrhea patient (adults and child) and their accompanying household members during the time of illness followed by two home visits during the 7-day high risk period for diarrheal disease transmission. The health promoter delivers a pictorial WASH module on how diarrhea can spread, and instructions on handwashing with soap, water treatment, and safe water storage. A diarrhea prevention package is provided containing: a one-month supply of chlorine tablets for water treatment, a soapy water bottle for handwashing, a handwashing station, and a water vessel with a lid and tap to ensure safe water storage. After health facility delivery of the program, patient households receive weekly voice and text messages from the PICHA7 mHealth program over 12 months on the recommended WASH behaviors.

OTHERStandard Arm

Standard message given in the Democratic Republic of the Congo to diarrhea patients at health facility discharge on use of oral rehydration solution


Locations(2)

General Provincial Reference Hospital of Bukavu

Bukavu, South Kivu, Democratic Republic of the Congo

Université Catholique de Bukavu

Bukavu, South Kivu, Democratic Republic of the Congo

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NCT05166850


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