Cholera Clinical Trials

10 recruitingLast updated: May 13, 2026

There are 10 actively recruiting cholera clinical trials across 6 countries. Studies span Not Applicable, Phase 4, Phase 2, Phase 3. Top locations include Dhaka, Bangladesh, Bukavu, South Kivu, Democratic Republic of the Congo, Durban, Eastern Cape, South Africa. Updated daily from ClinicalTrials.gov.


Cholera Trials at a Glance

10 actively recruiting trials for cholera are listed on ClinicalTrialsFinder across 6 cities in 6 countries. The largest study group is Not Applicable with 4 trials, with the heaviest enrollment activity in Dhaka, Bukavu, and Durban. Lead sponsors running cholera studies include Johns Hopkins Bloomberg School of Public Health, International Vaccine Institute, and Institut Pasteur du Cambodge.

Browse cholera trials by phase

Treatments under study

About Cholera Clinical Trials

Looking for clinical trials for Cholera? There are currently 5 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Cholera trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Cholera clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 110 of 10 trials

Recruiting
Not Applicable

Testing a Scalable Model of the Cholera Hospital-Based Intervention for 7 Days (CHoBI7)

Diarrhea InfectiousCholera
Johns Hopkins Bloomberg School of Public Health1,600 enrolled1 locationNCT06498817
Recruiting
Not Applicable

Vaccine- and Infection-derived Correlates of Protection for Cholera

Cholera
Massachusetts General Hospital1,221 enrolled1 locationNCT06455852
Recruiting
Phase 2

Age-descending Study to Evaluate the Safety and Immunogenicity of the Cholera Conjugate Vaccine in Adults and Children

Cholera Vaccination
International Vaccine Institute390 enrolled1 locationNCT07509047
Recruiting
Phase 4

Extended Dosing Intervals Trial for Oral Cholera Vaccine, Kenya

Cholera Vaccination
Albert B. Sabin Vaccine Institute1,071 enrolled1 locationNCT07487077
Recruiting

Risk Assessment of Community Spread of Multiple Endemic Infectious Diseases in a One Health Perspective

Streptococcus PneumoniaeMalariaMeningitis+55 more
Institut Pasteur du Cambodge10,000 enrolled1 locationNCT07358910
Recruiting
Phase 3

Trial to Evaluate Immunogenicity Non-Inferiority, Safety and Lot-to-Lot Consistency of Biovac OCV-S to Euvichol®-Plus

Cholera Vaccination
International Vaccine Institute2,824 enrolled5 locationsNCT07304284
Recruiting
Not Applicable

Preventative Intervention for Cholera for 7 Days

Diarrhea InfectiousCholeraWater-Related Diseases
Johns Hopkins Bloomberg School of Public Health2,900 enrolled2 locationsNCT05166850
Recruiting
Not Applicable

Cholera-Hospital-Based-Intervention-for-7-Days (CHoBI7) Water, Sanitation, and Hygiene (WASH) Case Area Targeted Intervention (CATI)

DiarrheaCholera
Johns Hopkins Bloomberg School of Public Health3,140 enrolled2 locationsNCT06003816
Recruiting
Phase 4

CVD 38000: Study of Responses to Vaccination With Typhoid and/or Cholera

Typhoid and/or Cholera Vaccination
University of Maryland, Baltimore240 enrolled1 locationNCT03705585
Recruiting

Impact Study of Cholera Vaccination in Endemic Areas - Clinical Surveillance

Cholera
Epicentre6,000 enrolled1 locationNCT04853186