RecruitingPhase 2NCT05178069

LGG Supplementation in Patients With AUD and ALD

Lactobacillus Rhamnosus GG: A Novel Probiotic Therapy for Treating Alcohol Use Disorder


Sponsor

University of Louisville

Enrollment

60 participants

Start Date

Jun 1, 2022

Study Type

INTERVENTIONAL

Conditions

Summary

To test the efficacy of 6-month LGG compared to placebo in treating Alcoholic Use Disorder (AUD) and liver injury in Alcoholic Hepatitis (AH). And to evaluate the effects of LGG treatment compared to placebo on therapeutic-mechanistic markers of the gut-brain axis and pro-inflammatory activity in patients with AUD and moderate AH


Eligibility

Min Age: 21 YearsMax Age: 65 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called : Placebo for Probiotic and Lactobacillus Rhamnosus GG for people with alcohol associated liver disease and alcohol use disorder. The study is currently recruiting participants at 1 location. People eligible for this study include aged 21 Years to 65 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUG: Placebo for Probiotic

Capsule manufactured without active ingredients.

DIETARY_SUPPLEMENTLactobacillus Rhamnosus GG

Probiotic nutritional supplement; Lactobacillus Rhamnosus G


Locations(1)

University of Louisville Hospital

Louisville, Kentucky, United States

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NCT05178069


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