RecruitingNCT05185141

Respiratory Variation of Carotid Doppler Peak Velocity (CDPV) for Non-invasive Prediction of Fluid Responsiveness

Assessing Respiratory Variation of Carotid Doppler Peak Velocity (CDPV) for Non-invasive Prediction of Fluid Responsiveness During Abdominal Surgery: a Prospective Observational Trial

Sponsor

Johannes Gutenberg University Mainz

Enrollment

84 participants

Start Date

Jan 11, 2022

Study Type

OBSERVATIONAL

Conditions

Hemodynamic Instability

Summary

The purpose of this study is to assess respiratory variation of carotid doppler peak velocity (∆CDPV) for prediction of fluid responsiveness during major abdominal surgery.

Eligibility

Min Age: 18 YearsMax Age: 80 Years

Inclusion Criteria3

Age 18-80 years
written informed consent
scheduled major abdominal surgery

Exclusion Criteria16

Age <18 or >80 years
pregnancy
SIRS or sepsis
any kind of cardiac arrhythmia
known valve disease
known heart failure
any kind of known carotid stenosis
carotid doppler peak velocity >182 cm/s before baseline measurement (expected stenosis)
missing indication for invasive arterial blood pressure monitoring (IBP) not related to the study
peripheral artery disease (PAD)
BMI > 35 kg/m2
intraabdominal hypertension
ASA-PSC of 4
severe lung disease (e.g. COPD grade 3, fibrosis)
esophageal disease of any kind
participation in another clinical study