Randomized Feasibility Trial for Mesh in Pre-Pectoral Reconstruction

This study is testing whether using a surgical mesh during pre-pectoral breast reconstruction (implant placed in front of the chest muscle after mastectomy) offers any benefit compared to reconstruction without mesh. The goal is to determine the best technique for this increasingly common procedure. **You may be eligible if...** - You are a woman between 22 and 75 years old - You are having a single or double mastectomy with immediate breast reconstruction using tissue expanders placed in front of the chest muscle (pre-pectoral) - Both preventive and cancer-related mastectomies are accepted - Nipple-sparing and skin-sparing techniques are both accepted **You may NOT be eligible if...** - Your surgeon finds the mastectomy skin flaps are too thin or unhealthy for immediate pre-pectoral reconstruction during surgery - You are having one breast reconstructed in front of the muscle and the other behind it - You are having a direct-to-implant reconstruction (skipping tissue expanders) - You are pregnant - You are having delayed reconstruction Talk to your doctor to see if this trial is right for you.