RecruitingNot ApplicableNCT05195385

Lung Cancer Screening With Low-dose CT Scan in Women : Implementation Study


Sponsor

Assistance Publique - Hôpitaux de Paris

Enrollment

2,635 participants

Start Date

Apr 8, 2022

Study Type

INTERVENTIONAL

Conditions

Summary

The purpose of this study is to determine whether reading of low-dose thoracic CT scans can be done by a single general radiologist who has been trained to lung cancer screening, and will evaluate the performance in comparison with double reading by experts. The study will enroll women between 50 and 74 years old, at risk for lung cancer due to their smoking history.


Eligibility

Sex: FEMALEMin Age: 50 YearsMax Age: 74 Years

Inclusion Criteria4

  • Women aged from 50 to 74 years
  • who had smoked at least 20 pack years and quit less than 15 years ago
  • Had given their consent and accepted the need for a 2-year follow-up
  • Affiliated to the social security system

Exclusion Criteria5

  • Presence of clinical symptoms suggesting malignancy (weight loss, hemoptysis) or ongoing infection (cough with fever)
  • Evolving cancer
  • History of lung cancer
  • A 2-year follow-up not possible
  • Chest CT scan performed within 2 years prior to inclusion

Interventions

PROCEDURELow-dose computed tomography of the chest

Baseline low dose Ct acquisition, then at 1 year and 2 years to depict suspicious lung nodules


Locations(1)

Hôtel-Dieu

Paris, France

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NCT05195385


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