RecruitingNot ApplicableNCT07408531

LUNG-07: Advancing Precision-Based Lung Cancer Screening: Implementation, AI-Guided Risk Stratification, and Biomarker Integration (CREST AI)


Sponsor

University of Illinois at Chicago

Enrollment

2,500 participants

Start Date

Mar 12, 2026

Study Type

INTERVENTIONAL

Conditions

Summary

This research study aims to investigate methods for enhancing lung cancer screening. The study will investigate whether an artificial intelligence (AI) tool, known as Sybil, can aid in predicting the risk of lung cancer. The investigators will also examine whether expanding the screening criteria (based on the guidelines of the Potter and American Cancer Society (ACS)) can help identify individuals at risk who are not currently included in the U.S. Preventive Services Task Force (USPSTF) guidelines.


Eligibility

Min Age: 50 YearsMax Age: 80 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying Sybil Artificial Intelligence (AI) screening for people with lung cancer screening. The study is currently recruiting participants at 2 locations. People eligible for this study include aged 50 Years to 80 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DIAGNOSTIC_TESTSybil Artificial Intelligence (AI) screening

Low-dose CT scans will be analyzed using the Sybil Artificial Intelligence (AI) screening tool


Locations(2)

UI Health

Chicago, Illinois, United States

UI Health 55th and Pulaski Health Collaborative

Chicago, Illinois, United States

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NCT07408531


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