A National Phase II Study of Proton Therapy in Hepatocellular Carcinoma

This national study is testing proton therapy — a precise form of radiation that targets tumors while sparing surrounding tissue — for patients with liver cancer (hepatocellular carcinoma, HCC) who cannot have surgery or standard ablation procedures. **You may be eligible if...** - You are 18 or older - You have been diagnosed with liver cancer (HCC) confirmed by imaging or biopsy - Your cancer is confined to the liver (no spread outside the liver) - You are not eligible for surgery or ablation, or you prefer not to have those procedures - You have no more than 3 tumors with a total diameter of 12 cm or less - Your liver function is adequate (Child-Pugh score of 8 or less) **You may NOT be eligible if...** - Your liver cancer has spread outside the liver - You have more than 3 liver tumors or very large tumors - Your liver function is severely impaired - You have had recent treatment that hasn't healed adequately Talk to your doctor to see if this trial is right for you.