RecruitingNot ApplicableNCT05227547

Mapping and Characterization of Alveolar Cells During Smoking and Chronic Obstructive Disease

Sponsor

Centre Hospitalier Intercommunal Creteil

Enrollment

186 participants

Start Date

Oct 5, 2022

Study Type

INTERVENTIONAL

Conditions

Chronic Obstructive Pulmonary Disease Chronic Obstructive Lung Disease

Summary

To evaluate the regenerative capacities of mesenchymal cells composing the microenvironment of alveolar type 2 cells in a population of patients, undergoing thoracic surgery for suspected cancer, who are smokers with and without COPD compared to non-smokers patients

Eligibility

Min Age: 18 Years

Inclusion Criteria4

Age ≥ 18
Patient undergoing lung resection surgery (lobectomy, pneumonectomy, segmentectomy) for cancer or suspected cancer
Acceptance to participate in the protocol
Affiliated to a social security plan

Exclusion Criteria8

Chronic autoimmune disease
Patient under guardianship or curators
Neo-adjuvant chemotherapy
History of thoracic radiotherapy
Pregnant woman
Minor patient
Person not able to consent
Person deprived of liberty

Interventions

OTHERThoracic resection surgery

Patients undergoing thoracic resection surgery (pneumonectomy, lobectomy, segmentectomy) for cancer or suspected cancer, including smokers (active or ex-smokers) and non-smokers, with COPD and without COPD, and non-smoking patients.