RecruitingPhase 2NCT05235919

Treatment to Promote Self-regulation in Children With Autism Spectrum Disorder

Repetitive Transcranial Magnetic Stimulation to Promote Helpful Self-regulatory Behaviour in Children and Youth With Autism Spectrum Disorder


Sponsor

Holland Bloorview Kids Rehabilitation Hospital

Enrollment

50 participants

Start Date

Sep 22, 2022

Study Type

INTERVENTIONAL

Conditions

Summary

This study will evaluate the feasibility of repetitive Transcranial Magnetic Stimulation (rTMS) in Autism Spectrum Disorder (ASD) with self-regulation impairment. Baseline and follow-up participant visits will include behavioral assessments of self-regulation and magnetic resonance imaging (MRI) to determine neurophysiological outcomes before and after rTMS treatment.


Eligibility

Min Age: 9 YearsMax Age: 18 Years

Inclusion Criteria2

  • Children with a diagnosis of autism spectrum disorder and self-regulation impairment or challenges
  • Able to participate in rTMS

Exclusion Criteria3

  • Children with autism spectrum disorder but no co-morbid self-regulation disorders.
  • Children with contraindications to TMS (history of seizures, family history of seizures, metal implants)
  • Co-existing neurological conditions (epilepsy, stroke, etc.)

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Interventions

DEVICErepetitive transcranial magnetic stimulation (rTMS)

30 minutes rTMS session 5 days/week for 3 weeks.

OTHERSham stimulation

30 minutes sham stimulation 5 days/week for 3 weeks.


Locations(1)

Bloorivew Research Institute

Toronto, Ontario, Canada

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NCT05235919


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