RecruitingNot ApplicableNCT06582225

ICBT for OCD in Children With Autism

Internet-delivered Cognitive-behaviour Therapy for Obsessive- Compulsive Disorder in Children With Autism: A Randomised Controlled Trial


Sponsor

Karolinska Institutet

Enrollment

220 participants

Start Date

Nov 25, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

The purpose of this trial is to evaluate the clinical efficacy, the cost-effectiveness and the effect durability of a therapist-guided, internet-delivered cognitive-behavior therapy intervention for obsessive-compulsive disorder (OCD) in children and adolescents with autism. A process evaluation of the treatment will also be conducted.


Eligibility

Min Age: 7 YearsMax Age: 17 Years

Plain Language Summary

Simplified for easier understanding

This study tests an internet-based cognitive behavioral therapy (ICBT) program — a structured, therapist-guided treatment delivered online — specifically adapted for children with both autism and OCD (obsessive-compulsive disorder). OCD is very common in autistic children but standard treatments often need to be modified to work well for them. **You may be eligible if...** - Your child has a formal diagnosis of autism (DSM or ICD criteria) - Your child has also been diagnosed with OCD - Your child is school-aged (specific age range confirmed at screening) - Your child's OCD causes meaningful distress or interference in daily life **You may NOT be eligible if...** - Your child's OCD symptoms are primarily caused by another medical condition - Your child has severe intellectual disability that would prevent participation - Your child is currently receiving another OCD treatment that could interfere Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

BEHAVIORALInternet-delivered exposure and response prevention (I-ERP)

The intervention is internet-delivered and therapist-guided, involving the child and at least one caregiver. It consists of two separate sets of modules, one for the child and one for the caregiver. The intervention consists of 12 modules, delivered over a maximum of 14 weeks. The treatment includes psychoeducation about ASD, OCD, emotions, healthy habits, the difference between repetitive behaviours in autism and OCD, how compulsions maintain the obsessions, and the rationale for ERP. The main focus of the treatment is ERP tasks based on the young person's individual goals. The modules also contain homework tasks that are meant to be completed between modules, mainly consisting of ERP. The final module includes a summary of the treatment and a relapse prevention plan. The version for parents consists of the same content as the child treatment, but with elaborated psychoeducation, and additional focus on strategies on how to assist their child in the different exposure tasks.

BEHAVIORALInternet-delivered stress management (I-SM)

The intervention is internet-delivered and therapist-guided, involving the child and at least one caregiver. It consists of two separate sets of modules, one for the child and one for the caregiver. The intervention consists of 12 modules, delivered over a maximum of 14 weeks. The treatment includes psychoeducation about ASD, OCD, healthy habits, and how stress is a contributor to OCD symptoms. The rationale is that targeting and reducing stress will have a beneficial impact on anxiety, obsessions, and compulsions. The main goal of the treatment is to learn how to reduce stress, mainly by using relaxation techniques such as deep breathing, progressive muscle relaxation, and imagery (cognitive) relaxation. The modules also contain homework tasks that are meant to be completed between modules, mainly consisting of relaxation tasks. The version for parents contains psychoeducation, as well as strategies on how to assist their child in the different relaxation tasks.


Locations(3)

Forskningsmottagning barn- och ungdomspsykiatri Lund

Lund, Skåne County, Sweden

Child and Adolescent Psychiatry Research Center

Stockholm, Stockholm County, Sweden

BUP Specialmottagning

Gothenburg, Västra Götalandsregionen, Sweden

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NCT06582225


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