RecruitingNot ApplicableNCT05235945

The Effect of Exercise in Patients Awaiting Bariatric Surgery

The Effect of a Preoperative Exercise Programme on Cardiorespiratory Fitness, Resting Metabolic Rate and Autonomic Control in Patients With Severe Obesity Awaiting Bariatric Surgery

Sponsor

University College, London

Enrollment

48 participants

Start Date

Jun 16, 2023

Study Type

INTERVENTIONAL

Conditions

Obesity Bariatric Surgery Candidate

Summary

The aim of this project is to understand the impact of a four week preoperative exercise programme on fitness and metabolic rate and weight before surgery. A multi-site randomised trial sponsored by UCL, recruiting patients awaiting bariatric surgery for obesity at University College London Hospital (UCLH), Whittington Health NHS Trust, or Homerton University Hospital NHS Foundation Trust. The investigators will measure fitness, metabolic rate, body weight/composition and grip strength in all participants, before and after a four-week supervised physical activity intervention. The investigators will also interview participants about their participation in the study in regard to the planning of future studies.

Eligibility

Min Age: 18 Years

Inclusion Criteria6

Adults, aged 18 and above.
Patients enrolled in the UCLH, Homerton or Whittington Hospitals bariatric surgery program with BMI > 30 kg/m2
≤5 % variation in body weight over preceding 3 months.
Willing and able to comply with the trial protocol.
Willing and able to provide written informed consent
Male or Female

Exclusion Criteria6

Pregnant or lactating mothers.
Weight over 180 kg (due to weight restrictions of equipment used).
Current use of betablockade.
Concurrent participation in other clinical intervention trial.
Clinically significant medical co-morbidities (e.g. uncontrolled hypertension, unstable cardiovascular disease) that could place at risk of an adverse response to exercise.
History of atrial fibrillation, unstable angina, acute coronary syndrome, congestive heart failure New York Heart Association class III-IV within the preceding 12 months.