Specialty Compared to Oncology Delivered Palliative Care for Patients With Acute Myeloid Leukemia
Massachusetts General Hospital
2,300 participants
Jun 1, 2022
INTERVENTIONAL
Conditions
Summary
This research study is evaluating whether primary palliative care is an alternative strategy to specialty palliative care for improving quality of life, symptoms, mood, coping, and end of life outcomes in patients with acute myeloid leukemia (AML).
Eligibility
Inclusion Criteria7
- Hospitalized patients (age ≥ 18 years) with high-risk AML defined as:
- Patients with new diagnosis ≥ 60 years of age
- An antecedent hematologic disorder
- Therapy related-disease
- Relapsed or primary refractory AML
- Within five business days of initiating therapy with either a) intensive chemotherapy (7+3) or modification of this regimen on a clinical trial, or a similar intensive regimen requiring prolonged hospitalization; or b) hypomethylating agents +/- additional agents or modification of this regimen on a clinical trial.
- Adult (≥18 years) relative or friend of a participating patient who the patient identifies as living with or has in-person contact with them at least twice per week.
Exclusion Criteria5
- Patients with a diagnosis of acute promyelocytic leukemia (APML)
- Patients with AML receiving supportive care alone
- Patients with psychiatric or cognitive conditions which the treating clinicians believe prohibits informed consent or compliance with study procedures
- Patients seen by a palliative care clinician (MD, DO, APP) during two previous hospitalizations in the six months prior to enrollment
- Patients expected to be discharged within 2 days
Interventions
Participants assigned to specialty palliative care will be cared for by both oncology and palliative care clinicians during their hospital stays for AML.
Participants assigned primary palliative care will be cared for by oncology clinicians who have been trained in palliative care during the hospital stays for AML.
Locations(20)
View Full Details on ClinicalTrials.gov
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NCT05237258