RecruitingNot ApplicableNCT06472128

Novel Digital Application for Patients With Acute Leukemia

Multi-Site Randomized Controlled Trial of a Novel Digital Application (DREAMLAND) to Improve Outcomes for Patients With Acute Myeloid Leukemia


Sponsor

Massachusetts General Hospital

Enrollment

200 participants

Start Date

Oct 21, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

This research study is evaluating to examine the efficacy of a novel a self-administered digital application (DREAMLAND) for improving patients' long-term quality of life and psychological outcomes for patients with acute myeloid leukemia undergoing intensive chemotherapy.


Eligibility

Min Age: 18 YearsMax Age: 120 Years

Inclusion Criteria4

  • Hospitalized patients (age \> 18 years) with a diagnosis of AML.
  • Initiating treatment with either a) intensive chemotherapy (7+3) or modification of this regimen on a clinical trial, or a similar intensive regimen or b) hypomethylating agents (HMA) +/- additional agents or modification of this regimen on a clinical trial.
  • Ability to comprehend and speak English as the digital apps are only available in English
  • Note: Patients newly diagnosed as well as those with relapsed/refractory AML initiating treatment with intensive or HMA-based chemotherapy will be eligible to participate.

Exclusion Criteria2

  • Patients with a diagnosis of acute promyelocytic leukemia
  • Patients with acute or unstable psychiatric or cognitive conditions which the treating clinicians believes prohibits informed consent or compliance with study procedures.

Interventions

BEHAVIORALDREAMLAND

Participants assigned to DREAMLAND will start using DREAMLAND during the first week of their hospitalization, with a suggested timeline of reviewing one module each week to complete the required modules by week 4 of their hospital stay.

BEHAVIORALVITAL WELLNESS

Participants assigned to VITAL WELLNESS will start using VITAL WELLNESS during the first week of their hospitalization, with a suggested timeline of reviewing one module each week to complete the required modules by week 4 of their hospital stay.


Locations(3)

Massachusetts General Hospital (MGH)

Boston, Massachusetts, United States

Duke University

Durham, North Carolina, United States

Fred Hutchinson Cancer Research Center (FHCRC)

Seattle, Washington, United States

View Full Details on ClinicalTrials.gov

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NCT06472128


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