RecruitingNot ApplicableNCT05246527

Acute Effects of Physical Exercise in Patients with Borderline Personality Disorder


Sponsor

University Hospital, Bonn

Enrollment

120 participants

Start Date

Feb 8, 2022

Study Type

INTERVENTIONAL

Conditions

Summary

The aim of the proposed project is to investigate the effects of a single session of physical exercise on stress regulation, cognitive and emotional functioning, and associated neurophysiological processes (saliva and blood samples) in patients with borderline personality disorder. A further aim is to identify the optimal exercise intensity (moderate vs. high intensity). The investigatiors expect that acute exercise will lead to positive effects on behavioral and biomarker level.


Eligibility

Min Age: 18 YearsMax Age: 50 Years

Inclusion Criteria2

  • estimated verbal intelligence quotient >80 (MWT-B; Lehrl 2005)
  • patients: diagnosis of borderline personality disorder according to DSM-5

Exclusion Criteria6

  • neurological disorders
  • health conditions interfering with exercise safety, e.g. coronary heart disease
  • visual impairments that may interfere with performance of the cognitive tasks
  • endocrine disorders, e.g. hyperthyreosis or diabetes mellitus;
  • following psychiatric disorders: psychosis or affective disorders with psychotic symptoms, schizophrenia, substance abuse or dependence, autism spectrum disorders, anorexia nervosa;
  • healthy controls: BPD, intake of psychotropic drugs

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Interventions

BEHAVIORALPhysical Exercise

30 min of cycling on an ergometer, moderate or high intensity

BEHAVIORALControl Intervention

30 min of watching a movie


Locations(1)

University Hospital Bonn

Bonn, North Rhine-Westphalia, Germany

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NCT05246527


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