RecruitingNCT05250349

TRAnscranial Doppler CErebral Blood Flow and Cognitive IMPAIRment in Heart Failure

TRAnscranial Doppler CErebral Blood Flow and Cognitive IMPAIRment in Patients With Heart Failure and Presence/Absence of Atherosclerotic Carotid Artery Stenosis

Sponsor

John Paul II Hospital, Krakow

Enrollment

300 participants

Start Date

Sep 1, 2021

Study Type

OBSERVATIONAL

Conditions

Heart Failure Cognitive Impairment Carotid Stenosis

Summary

TRACE-IMPAIR is a prospective, clinical study of consecutive patients that evaluates the relationship between heart failure (HF) and cognitive impairment in relation to carotid and cerebral flow. The carotid and cerebral flow will be assessed using Doppler ultrasonography, and cognitive function will be estimated during routine neuropsychological tests. It is an observational, three(natural)-group, single-center study. It is also an Academic Registry - the scientific activity of the Faculty of Medicine, Collegium Medicum, Jagiellonian University, and John Paul II Hospital.

Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is investigating whether reduced blood flow to the brain may explain the memory and thinking problems that many people with heart failure experience. Researchers will use ultrasound-based brain blood flow measurements alongside thinking tests to look for a link between heart function and brain health. **You may be eligible if...** - You have been diagnosed with heart failure for at least 6 months and are currently stable - Your heart failure is due to coronary artery disease, inflammation, or a genetic condition - You are willing to undergo ultrasound studies and thinking tests **You may NOT be eligible if...** - You have severe, irreversible disease such as advanced cancer - You have already been diagnosed with moderate to severe dementia - You have a psychiatric condition that affects thinking - You are in acute, decompensated heart failure - You had a stroke within the last 3 months - You have severe anemia (hemoglobin below 8 g/dL) - You abuse alcohol or psychoactive substances Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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