Safety and Efficacy of Human Microbiota Transplantation for Overweight and Obese Type 2 Diabetes Mellitus

This study is testing whether a fecal microbiota transplant (FMT) — transferring gut bacteria from a healthy donor — can help improve blood sugar control in people who are overweight or obese and have type 2 diabetes. Researchers believe that changing the balance of gut bacteria may improve how the body responds to insulin. **You may be eligible if...** - You have been diagnosed with type 2 diabetes for at least 2 months - You are currently managing your blood sugar only through diet and exercise, without medication for the last 8 weeks - Your HbA1c (a 3-month blood sugar average) is between 7.0% and 10.0% - Your BMI is between 24 and 35 (overweight to obese range) - You are willing to maintain your usual diet and exercise habits throughout the study **You may NOT be eligible if...** - You have type 1 diabetes, gestational diabetes, or another special type of diabetes - You have gastrointestinal conditions such as IBS or inflammatory bowel disease - You are pregnant - You have serious uncontrolled health conditions - You have recently taken antibiotics or medications that affect the gut Talk to your doctor to see if this trial is right for you.