Type 2 Diabetes Mellitus Clinical Trials

45 recruiting

Frequently Asked Questions

Common questions about Type 2 Diabetes Mellitus clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 137 trials

Recruiting

An Observational Study Called FINE-REAL Korea to Learn More About the Use of the Drug Finerenone in People With Chronic Kidney Disease and Type 2 Diabetes in a Routine Medical Care Setting in South Korea

Chronic Kidney DiseaseType 2 Diabetes Mellitus
Bayer500 enrolled1 locationNCT07232537
Recruiting
Phase 1

A Study of REGEND003 on Patients With Type 2 Diabetes Mellitus (T2DM) and Chronic Kidney Disease (CKD)

Type 2 Diabetes Mellitus (T2DM) and Chronic Kidney Disease (CKD)
Regend Therapeutics15 enrolled1 locationNCT07275788
Recruiting
Not Applicable

Using Continuous Glucose Monitoring to Quantify the Effects of NOURISH's Culturally Modified Meals on Asian Americans With Type 2 Diabetes

Type 2 Diabetes Mellitus (T2DM)Type 2 Diabetes
Stanford University30 enrolled1 locationNCT06836479
Recruiting
Phase 3

A Clinical Study to Evaluate the Effects of RO7795068 in Participants With Obesity or Overweight and Type 2 Diabetes

Obesity or OverweightType 2 Diabetes Mellitus
Hoffmann-La Roche1,600 enrolled3 locationsNCT07351058
Recruiting
Not Applicable

Implementation pRogram to Improve Screening and Management for CKD in Diabetes (Program 1) (IRIS-CKD)

Type 2 Diabetes Mellitus (T2DM)Chronic Kidney Disease(CKD)Type 2 DM
Duke University750 enrolled6 locationsNCT06906627
Recruiting
Not Applicable

Implementation pRogram to Improve Screening and Management for CKD in Diabetes (IRIS-CKD) (Program 2)

Type 2 Diabetes Mellitus (T2DM)Chronic Kidney Disease(CKD)Type 2 DM
Duke University420 enrolled6 locationsNCT06906640
Recruiting
Phase 1

A Study to Evaluate the Effect of RO7204239 on Insulin Sensitivity and Muscle Composition in Participants With Type 2 Diabetes Mellitus (T2DM) and Overweight or Obesity

ObesityOverweightType 2 Diabetes Mellitus
Hoffmann-La Roche30 enrolled1 locationNCT07137585
Recruiting
Phase 2

A Study to Compare Different Doses of RO7795081 With a Placebo or Semaglutide in People With Type 2 Diabetes

Type 2 Diabetes Mellitus
Hoffmann-La Roche240 enrolled51 locationsNCT07112872
Recruiting
Not Applicable

Clinical Study to Evaluate the Impact of the Accu-Chek SmartGuide CGM Solution on the Mean Change in Time in Range Compared With Self-Monitoring of Blood Glucose in Participants With Type 1 and Type 2 Diabetes Mellitus

Type 1 Diabetes MellitusType 2 Diabetes Mellitus
Hoffmann-La Roche270 enrolled14 locationsNCT06704672
Recruiting

Investigation of Motor Imagery Ability, Body Awareness and Cognitive Functions in Type 2 Diabetes Mellitus

Cognitive FunctionType 2 Diabetes Mellitus (T2DM)Motor İmagery Ability
Kutahya Health Sciences University100 enrolled1 locationNCT06588894
Recruiting
Phase 2

A Study to Evaluate ALN-4324 on Insulin Sensitivity in Adults With Type 2 Diabetes Mellitus

Type 2 Diabetes Mellitus (T2DM)
Alnylam Pharmaceuticals40 enrolled1 locationNCT07465224
Recruiting
Not Applicable

Achieving Routine Intervention and Screening for Emotional Health

Type 2 Diabetes Mellitus (T2DM)Diabetes Distress
University of Chicago1,250 enrolled1 locationNCT06887049
Recruiting
Not Applicable

Continuous Glucose Monitoring for Outpatient Diabetes Management After Hospital Discharge

Type 1 Diabetes Mellitus (T1DM)Type 2 Diabetes Mellitus (T2DM)Hyperglycemia
Vanderbilt University Medical Center60 enrolled1 locationNCT06852950
Recruiting
Not Applicable

Clinical Management of Cardiovascular Risk Factors in Adult Patients: A Before-and-After Interventional Study

ObesityHypertensionOverweight+4 more
Universidad Católica San Antonio de Murcia220 enrolled1 locationNCT07447362
Recruiting
Phase 4

Glycemic Variability of Combination Therapies in T2DM

Type 2 Diabetes Mellitus (T2DM)
JW Pharmaceutical178 enrolled1 locationNCT07442006
Recruiting
Not Applicable

Human Immunodeficiency Virus (HIV) Food Insecurities

Type 2 Diabetes Mellitus (T2DM)PrediabetesHIV+2 more
Wake Forest University Health Sciences200 enrolled1 locationNCT04943861
Recruiting
Phase 1Phase 2

A Study to Evaluate ALN-4324 in Overweight to Obese Healthy Volunteers and in Overweight to Obese Patients With T2DM

Type 2 Diabetes Mellitus (T2DM)Obese or Overweight Healthy Volunteers
Alnylam Pharmaceuticals144 enrolled2 locationsNCT06845202
Recruiting
Not Applicable

Para-Probiotic Oral Care in Periodontal Patients With Type 2 Diabetes

Type 2 Diabetes Mellitus (T2DM)Periodontitis
University of Pavia40 enrolled1 locationNCT07069166
Recruiting
Phase 1

A Study to Evaluate the Effect of AZD6793 on the Pharmacokinetics and Pharmacodynamics of Metformin in Participants With Type 2 Diabetes Mellitus

Type 2 Diabetes Mellitus
AstraZeneca28 enrolled1 locationNCT07433062
Recruiting

Dietary Insights and Nutrition Experiences in Adults on GLP-1 Therapy - A Study on Diet Quality Changes in Adults on GLP-1 Therapy

Obesity (Disorder)Obesity Type 2 Diabetes Mellitus
University of South Carolina50 enrolled2 locationsNCT07313384