RecruitingNot ApplicableNCT05254431

The Effect of Interval Exercise on Functional Outcomes in Veterans With COPD and OSA

Sponsor

VA Office of Research and Development

Enrollment

28 participants

Start Date

Apr 1, 2022

Study Type

INTERVENTIONAL

Conditions

COPD OSA

Summary

The term "Overlap Syndrome" (OS) is used to describe the presence of both chronic obstructive pulmonary disease (COPD) and obstructive sleep apnea (OSA) in a single patient. Due to premature aging, patients with OS are prone to developing functional decline up to 20 years earlier than the general population. The International Classification of Functioning, Disability and Health (ICF) evaluates functional status in chronic pulmonary disease globally in 5 domains. The investigators propose to study validated outcomes in 3 of these domains: 1) participation in life situations; 2) physical activity; and 3) cardiovascular health. The investigators long-term goal is to develop an exercise strategy tailored to Veterans with OS which will reduce the risk of functional decline through increased PA.

Eligibility

Plain Language Summary

Simplified for easier understanding

This study is testing whether interval exercise training — alternating between bursts of activity and rest — can improve physical function and quality of life in veterans who have both COPD (a chronic lung disease) and sleep apnea (OSA). Having both conditions at the same time, called "overlap syndrome," makes exercise particularly challenging. **You may be eligible if...** - You are a veteran diagnosed with both COPD and sleep apnea (overlap syndrome) - Your diagnosis was confirmed by breathing tests and a sleep study - You scored above 20 on a standard cognitive screening test **You may NOT be eligible if...** - You have coronary artery disease (history of bypass surgery, a prior positive stress test, or angina) - You have joint pain that limits your ability to walk - You have fallen more than twice in the past month - You were hospitalized in the past month - You require supplemental oxygen at home during the day - You already exercise at a moderate or strenuous level regularly Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

BEHAVIORALExercise

Novel Moderate Intensity Interval Exercise The Experimental Design is a randomized trial of moderate intensity interval training (5-minute intervals at 50% VO2peak 3 times weekly for 12 weeks) in Veterans with COPD and OSA compared with standard of care controls