A Clinico-biological Database in Cachexia in Patients With Colon Cancer

This study is building a database of biological samples and health information from people with colon cancer who cannot have surgery. The goal is to better understand cachexia — the severe weight loss and muscle wasting that often happens with advanced cancer — and find better ways to track and treat it. **You may be eligible if...** - You are 18 years or older - You have colon cancer that cannot be treated with surgery - You are receiving or about to receive treatment (such as chemotherapy or targeted therapy) for your colon cancer - You are willing to provide blood samples as scheduled - You have signed an informed consent form **You may NOT be eligible if...** - You need surgery to treat your colon cancer or its spread - Your cancer has only spread to the lining of the abdomen (peritoneal carcinomatosis) - You require radiotherapy - You are unable to understand or follow the study instructions due to psychological, family, or other issues Talk to your doctor to see if this trial is right for you.