Colon Cancer Clinical Trials

106 recruiting

Colon Cancer Trials at a Glance

155 actively recruiting trials for colon cancer are listed on ClinicalTrialsFinder across 6 cities in 33 countries. The largest study group is Not Applicable with 60 trials, with the heaviest enrollment activity in Los Angeles, Boston, and Houston. Lead sponsors running colon cancer studies include National Cancer Institute (NCI), Chongqing Precision Biotech Co., Ltd, and Institut du Cancer de Montpellier - Val d'Aurelle.

Browse colon cancer trials by phase

Treatments under study

About Colon Cancer Clinical Trials

Looking for clinical trials for Colon Cancer? There are currently 106 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Colon Cancer trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Colon Cancer clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 155 trials

Recruiting

Genomic Services Research Program

Breast CancerColon Cancer
National Human Genome Research Institute (NHGRI)5,000 enrolled1 locationNCT02595957
Recruiting
Phase 1

Safety and Tolerability of ²¹²Pb-DOTAM-GRPR1 in Adult Subjects With Recurrent or Metastatic GRPR-expressing Tumors

Breast CancerCervical CancerColon Cancer+4 more
Orano Med LLC48 enrolled4 locationsNCT05283330
Recruiting
Phase 3

Identification and Treatment Of Micrometastatic Disease in Stage III Colon Cancer

Metastatic Colon CancerStage III Colon Cancer
Massachusetts General Hospital400 enrolled3 locationsNCT03803553
Recruiting
Phase 1Phase 2

Administering Peripheral Blood Lymphocytes Transduced With a Murine T-Cell Receptor Recognizing the G12V Variant of Mutated RAS in HLA-A*11:01 Patients

Pancreatic CancerGastric CancerColon Cancer+2 more
National Cancer Institute (NCI)110 enrolled1 locationNCT03190941
Recruiting

Acute Colon Resection Versus Bridge to Colon Surgery With Stent or Stoma

Colon Cancer
Skane University Hospital1,000 enrolled1 locationNCT04450758
Recruiting
Phase 2Phase 3

Colon Adjuvant Chemotherapy Based on Evaluation of Residual Disease

Stage III Colon Cancer
NRG Oncology1,912 enrolled1054 locationsNCT05174169
Recruiting
Phase 3

Neoadjuvant/Adjuvant AK104 in Microsatellite Instability-high or Mismatch Repair-deficient, Resectable Colon Cancer

MSI-H/dMMR Colorectal CancerResectable Colon Cancer
Akeso386 enrolled1 locationNCT07412613
Recruiting

Collection of Blood From Patients With Cancer

Breast CancerLiver CancerProstate Cancer+2 more
National Cancer Institute (NCI)1,750 enrolled1 locationNCT00034216
Recruiting
Phase 1

A Study of PHN-012 in Patients With Advanced Solid Tumors

Pancreatic CancerColon CancerAdvanced Cancer+2 more
Pheon Therapeutics165 enrolled21 locationsNCT07127874
Recruiting
Phase 2

Zanidatamab Before Surgery for the Treatment of HER2 Positive Colon and Rectal Cancer in Patients Planned for Curative Intent Treatment

Colorectal CarcinomaStage I Colorectal Cancer AJCC v8Stage II Colorectal Cancer AJCC v8+9 more
Emory University38 enrolled4 locationsNCT07405476
Recruiting
Not Applicable

Mechanical Bowel Preparation in Laparoscopic Right Hemicolectomy With Intracorporeal Anastomosis

Colon Cancer
University Medical Center Ho Chi Minh City (UMC)74 enrolled1 locationNCT07546565
Recruiting
Not Applicable

NIMA-Colon Cancer Study

Colon Cancer
Fundación Pública Andaluza para la Investigación de Málaga en Biomedicina y Salud120 enrolled1 locationNCT07534852
Recruiting
Phase 1

Testing the Combination of Two Anti-cancer Drugs, DS-8201a and AZD6738, for The Treatment of Advanced Solid Tumors Expressing the HER2 Protein or Gene, The DASH Trial

Anatomic Stage III Breast Cancer AJCC v8Anatomic Stage IV Breast Cancer AJCC v8Metastatic Breast Carcinoma+37 more
National Cancer Institute (NCI)51 enrolled23 locationsNCT04704661
Recruiting
Not Applicable

Electrochemotherapy (ECT) in Patients With Primary Visceral Tumors and/or Secondary Visceral Localizations, of Any Histotype

Liver CancerMelanomaMerkel Cell Carcinoma+9 more
Istituto Oncologico Veneto IRCCS24 enrolled1 locationNCT06753136
Recruiting

Follow-Up Study of Subjects Previously Enrolled in Poxviral Vector Gene Transfer Studies

Breast CancerLiver CancerProstate Cancer+2 more
National Cancer Institute (NCI)750 enrolled1 locationNCT00451022
Recruiting
Not Applicable

Designing a Dyad-Based mHealth Intervention to Improve Adherence to Lifestyle Recommendations in Colorectal Cancer Survivors and Their Family Caregivers

Stage III Colon Cancer AJCC v8Stage II Rectal Cancer AJCC v8Stage III Rectal Cancer AJCC v8+3 more
Ohio State University Comprehensive Cancer Center70 enrolled1 locationNCT06746012
Recruiting
Not Applicable

Survivors Uniting for Remote Guided Exercise

CancerCancer (Colon Cancer, Breast Cancer, Lymphoma, Chronic Lymphoma Leukemia, Multiple Myeloma)Physical Activity+4 more
Colorado State University300 enrolled1 locationNCT07290309
Recruiting

Leakage Rate of Ileo-COlic Sutured Anastomosis After Right Hemicolectomy

Colon CancerAnastomotic LeakRight Hemicolectomy
Aesculap AG249 enrolled3 locationsNCT07132970
Recruiting

Cancer Loyalty Card Study 2 (CLOCS-2)

Liver CancerPancreatic CancerOvarian Cancer+7 more
Imperial College London2,900 enrolled1 locationNCT06447064
Recruiting

Avera Cancer Sequencing and Analytics Protocol (ASAP)

Breast CancerOvarian CancerEndometrial Cancer+9 more
Avera McKennan Hospital & University Health Center25,000 enrolled6 locationsNCT05142033