RecruitingNCT05258448

COr Loco-regional Advanced Lung Cancer Treated With Chemo-radiotherapy (COLA)

The Effect of Radiotherapy on the Heart in Loco-regional Advanced NSCLC Patients Treated With Definitive Radiotherapy Measured by Cardiac MR

Sponsor

Odense University Hospital

Enrollment

100 participants

Start Date

Aug 1, 2015

Study Type

OBSERVATIONAL

Conditions

Radiation Toxicity Cardiac Toxicity Lung Cancer Stage II Lung Cancer Stage III Cardiac Disease

Summary

Patients with loco-regional NSCLC planned for curative treatment with chemoradiotherapy will be invited to participate in a prospective study; besides routine treatment, the patients will be followed with an ECG and cardiac MR for at least two years after radiotherapy treatment.

Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is looking at the effects of radiation therapy on the heart in people with locally advanced lung cancer. Researchers will use heart MRI and ECG tests before and after treatment to detect any changes in heart function caused by chemoradiotherapy. **You may be eligible if...** - You are 18 years or older - You have been diagnosed with non-small cell lung cancer (NSCLC) that cannot be surgically removed, confirmed by biopsy - You are planned to receive chemoradiotherapy with the goal of curing your cancer - You are able to complete ECG and heart MRI tests **You may NOT be eligible if...** - You have a pacemaker, implantable defibrillator, cochlear implant, or any device that makes MRI unsafe - You are claustrophobic - You are considered a vulnerable patient (unable to consent or at special risk) Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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