RecruitingNCT05265429

Biology of Young Lung Cancer Study: The YOUNG LUNG Study

Sponsor

Dana-Farber Cancer Institute

Enrollment

500 participants

Start Date

Jan 1, 2023

Study Type

OBSERVATIONAL

Conditions

Non-small Cell Lung Cancer Small Cell Lung Carcinoma NUT Carcinoma

Summary

The purpose of this research study is to learn more about lung cancer (NSCLC or SCLC) diagnosed in adults at ages 45 or younger.

Eligibility

Min Age: 15 Years

Plain Language Summary

Simplified for easier understanding

This study is collecting blood samples and tumor tissue from young adults (45 and under) diagnosed with lung cancer to understand why lung cancer sometimes occurs in younger people who may not have traditional risk factors like long-term smoking. This research could lead to better screening tools and treatments for this group. **You may be eligible if...** - You were 45 years old or younger when you were diagnosed with lung cancer - Your lung cancer has been confirmed by pathology (either NSCLC or SCLC, any stage) - You are willing to provide up to two blood draws within a 4-week period - Children under 18 may also be eligible with a parent or guardian's consent **You may NOT be eligible if...** - You decline to sign the consent form - You are unable to give consent and have no designated healthcare proxy - Using your tissue for research would interfere with your own diagnosis or staging Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

GENETICData and Specimen Collection

* Provide research team access to relevant medical records * Answer two (2) short questionnaires at time of consent * Provide up to 5 tubes (37 ml) of blood at or near the time of consent, and/or saliva sample * Consider consenting to other optional parts of the research such as: * Providing additional blood or tissue samples in the future (optional) * Providing permission for obtainment of stored tissue specimens from lung cancer surgeries or biopsies from the pathology departments where they have been stored (optional)