RecruitingNCT05281887

Correlation Between the Changes of Retinal Structure and Function and Ischemic Stroke


Sponsor

Guangdong Provincial People's Hospital

Enrollment

120 participants

Start Date

Dec 1, 2021

Study Type

OBSERVATIONAL

Conditions

Summary

Ischemic stroke is the most common type of stroke, accounting for 60%-80% of all types of strokes, and is one of the leading global causes of death and severe disability. In the risk factors of stroke, carotid atherosclerosis have higher incidence.As the only visible microvessels in vivo, retinal can provides an accurate window into cerebrovascular and systemic vascular conditions. Optical coherence tomography angiography (OCTA) and electroretinogram (ERG) can be used to quantitatively analyze the retinal structure and function in patients with ischemic stroke, and find out the valuable parameters. Electroencephalogram(EEG) can collect the electrical activity of cerebral cortex in patients with ischemic stroke and find the correlation between EEG and ERG. Finally, it is of great significance to establish a non-invasive, more objective, convenient and safe risk prediction model for stroke in combination with carotid atherosclerosis, retinal structural and functional parameters and EEG.


Eligibility

Min Age: 18 Years

Inclusion Criteria1

  • Patients with ischemic stroke

Exclusion Criteria4

  • Refractive interstitial turbidity affect the examination results
  • Any retinal diseases
  • Other causes of ischemic stroke (cardiogenic embolism, dissection aneurysm, hemagglutination disorder, polycythemia, vasculitis, vascular malformation, etc.)
  • Fails to complete an ophthalmic examination or the follow-up

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Locations(1)

Guangdong Provincial People's Hospital

Guangzhou, Guangdong, China

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NCT05281887


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