Targeting Cognition in Early Alzheimer's Disease by Improving Sleep With Trazodone

This study tests whether a low dose of the antidepressant trazodone, used as a sleep aid, can improve memory and slow cognitive decline in people with early Alzheimer's disease. Many people with early Alzheimer's have poor sleep, and researchers believe improving sleep quality might help protect the brain. **You may be eligible if...** - You are 55 or older with mild cognitive impairment (early memory problems that haven't reached full dementia) - You have sleep problems (poor sleep quality score above 5) - A family member or close friend who knows you well can participate alongside you in the study - You are healthy enough to tolerate MRI scans **You may NOT be eligible if...** - You have a diagnosis of full dementia - You are already taking sleep medications, including trazodone - You have moderate to severe sleep apnea (detected by a home sleep test) - You have a known allergy to trazodone - You currently abuse alcohol or drugs - You have a current major depressive episode or active psychosis Talk to your doctor to see if this trial is right for you.