Sleep Disturbance Clinical Trials

72 recruitingLast updated: June 17, 2026

There are 72 actively recruiting sleep disturbance clinical trials across 17 countries. Studies span Not Applicable, Phase 2, Phase 4, Phase 3. Top locations include Pittsburgh, Pennsylvania, United States, Chicago, Illinois, United States, Baltimore, Maryland, United States. Updated daily from ClinicalTrials.gov.


Sleep Disturbance Trials at a Glance

72 actively recruiting trials for sleep disturbance are listed on ClinicalTrialsFinder across 6 cities in 17 countries. The largest study group is Not Applicable with 52 trials, with the heaviest enrollment activity in Pittsburgh, Chicago, and Baltimore. Lead sponsors running sleep disturbance studies include University of Pittsburgh, Chinese University of Hong Kong, and Johns Hopkins University.

Browse sleep disturbance trials by phase

Treatments under study

About Sleep Disturbance Clinical Trials

Looking for clinical trials for Sleep Disturbance? There are currently 60 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Sleep Disturbance trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Sleep Disturbance clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 72 trials

Recruiting
Not Applicable

Transdiagnostic Sleep and Circadian Intervention + Bright Light in Adolescents With Elevated Depression (TranS-C+BL)

DepressionSleepSleep Disturbance+1 more
University of Pittsburgh90 enrolled2 locationsNCT06963463
Recruiting
Not Applicable

Self-Acupressure and Social Jet Lag in Female Health Sciences Students

circadian rhythm disruptionSleep QualitySleep Disturbance+1 more
Nigde Omer Halisdemir University120 enrolled1 locationNCT07410936
Recruiting
Phase 2

Nuestro Sueno: Cultural Adaptation of a Couples Intervention to Improve PAP Adherence and Sleep Health Among Latino Couples With Implications for Alzheimer's Disease Risk

Sleep DisturbanceSleep Apnea
University of Utah80 enrolled2 locationsNCT06649929
Recruiting
Not Applicable

Effects of Latin Dancing on Sleep Quality in Hispanic Cancer Survivors

Cancer SurvivorshipSleep Disturbances
Rutgers, The State University of New Jersey40 enrolled1 locationNCT06844981
Recruiting

Medications for Opioid Use Disorder Photosensitive Retinal Ganglion Cell Function, Sleep, and Circadian Rhythms: Implications for Treatment

Sleep DisturbanceOpioid-use Disorder
University of Alabama at Birmingham200 enrolled1 locationNCT06104280
Recruiting
Not Applicable

Differences in Rest, Emotion, and Arousal Modulation in Youth

SleepAutismSleep Disturbances in Children
University of Pittsburgh60 enrolled1 locationNCT07476937
Recruiting

Sleep Quality in Assisted-Living Residents

Sleep DisturbanceAging
University of Calgary150 enrolled1 locationNCT04400617
Recruiting
Phase 4

Using Dupilumab to Improve Circadian Function, Sleep and Pruritus in Children With Moderate/Severe Atopic Dermatitis

Sleep DisturbanceAtopic Dermatitis
Northwestern University40 enrolled1 locationNCT05042258
Recruiting
Not Applicable

RCT of a Weighted Blanket to Reduce Pain in Veterans With Chronic Pain

Sleep DisturbanceChronic Pain
VA Office of Research and Development160 enrolled2 locationsNCT05963607
Recruiting
Not Applicable

Home Apnea Testing in CHildren Trial

Sleep DisturbanceSleep DisorderSleep Apnea, Obstructive+1 more
Children's Hospital of Philadelphia317 enrolled1 locationNCT05382754
Recruiting
Phase 4

The Effect of Nocturnal Dexmedetomidine on Postoperative Sleep Quality and Fatigue After Major Surgery in Elderly Patients: DEXSLEEP Study

surgical stress responsePostoperative FatiguePostoperative Sleep Disturbances
Ziekenhuis Oost-Limburg102 enrolled1 locationNCT06480539
Recruiting
Not Applicable

Decentralized Clinical Trial of Effectiveness of EnergyPoints App in Cancer Survivors

Fatigue in Cancer SurvivorsHealth-related Quality of LifeSleep Disturbances+1 more
5 Point App, Inc.180 enrolled1 locationNCT06754722
Recruiting
Not Applicable

Sleep Optimization With Acoustic Therapy

Sleep DisturbanceIMSOMNIA
National University of Malaysia40 enrolled1 locationNCT07503223
Recruiting
Not Applicable

Prevention of Insomnia Using a Stepped Care Model in Adults

Sleep Disturbance
Chinese University of Hong Kong1,016 enrolled1 locationNCT06156293
Recruiting
Not Applicable

PICU-related Sleep and Circadian Dysregulation Pilot Study

Sleep DisturbanceCritical IllnessChildren, Only+1 more
State University of New York at Buffalo30 enrolled1 locationNCT06505447
Recruiting
Not Applicable

Virtual vs Physical Art Therapy for Anxiety, Psychological Well-being, and Sleep Quality in Colorectal Cancer Patients

AnxietySleep DisturbanceColorectal Cancer (Diagnosis)
Dokuz Eylul University78 enrolled1 locationNCT07464626
Recruiting
Not Applicable

VR-PMR for Post-Burn Symptoms

Virtual RealityAnxietyDepressive Symptoms+8 more
Johns Hopkins University34 enrolled1 locationNCT07317271
Recruiting
Not Applicable

Sleep Promotion Program Primary Care

SleepSleep DisturbanceInsufficient Sleep
University of Pittsburgh100 enrolled1 locationNCT06240325
Recruiting
Not Applicable

Sleep Enhancement for Older Adults Living With Memory Loss And Their Care Partners

DementiaSleep Disturbance
Emory University80 enrolled1 locationNCT06250725
Recruiting
Not Applicable

Wellness App for Sleep Disturbance in Hematological Cancer Patients

CancerDepressionFatigue+3 more
The University of Texas Health Science Center at San Antonio276 enrolled3 locationsNCT05294991