RecruitingNot ApplicableNCT05283369

Changes in Motor Function and Brain Connectivity on Subacute Stroke Patients, Associated With Videogame Therapy

Changes in Motor Function and Functional Brain Connectivity on Subacute Ischemic Stroke Patients, Associated With a New Videogame Therapy Platform


Sponsor

Universidad Nacional Autonoma de Mexico

Enrollment

60 participants

Start Date

Dec 2, 2022

Study Type

INTERVENTIONAL

Conditions

Summary

The use of interactive applications associated with movement sensors has begun to spread as an option for the reinforcement of physical rehabilitation therapies in patients with acquired motor disabilities as a consequence of some neurological damage, due to their portability and the relative autonomy that they grant to the patient. However, the results of its effectiveness and impact continue to be discreet compared to traditional therapy. The present study aims to explore possible changes in motor function and in the brain's functional connectivity through resting-state functional Magnetic Resonance Imaging (rs-fMRI), for subacute ischemic stroke outpatients, associated with occupational therapy using interactive applications as a therapeutic complement, comparing with patients on conventional therapy, for which a randomized pilot study with an experimental group and a matched control group will be carried out. The intervention will consist of the application of a virtual rehabilitation program in addition to physical therapy for the experimental group, while the control group will receive conventional physical therapy. Before and after the said intervention, standardized tests will be applied to evaluate the mobility, motor function, and cognitive impairment of the participants. The results obtained will be subject to statistical analysis.


Eligibility

Min Age: 18 YearsMax Age: 90 Years

Inclusion Criteria4

  • Upper extremity hemiparesis caused by ischemic stroke on its dominant side or not
  • In the subacute phase. From 2 to 16 weeks of ischemic stroke event
  • Fugl-Meyer Upper Extremity > 15
  • No previous stroke

Exclusion Criteria9

  • Token Test < 17. Inability to understand verbal instructions
  • Instability of the shoulder, elbow, or wrist joints
  • Severe concomitant medical problems such as congestive heart failure or seizures
  • Anosognosia
  • Severe aphasia
  • Hemispatial neglect
  • Visual impairments that are not corrected with glasses
  • Uncompensated hearing impairment
  • Patients receiving concomitant therapies

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Interventions

DEVICEVideogame therapy

The usual dose of conventional physical therapy, plus 300 minutes a week of in-home videogame therapy for 8 weeks.

OTHERConventional therapy

The usual dose of physical and occupational therapy, for 8 weeks.


Locations(1)

Ana María Escalante-Gonzalbo

Mexico City, Tlalpan, CDMX, Mexico

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NCT05283369


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