The Efficacy of Aspirin Combined With Hydroxychloroquine Treatment in High Risk Pregnancies for Preeclampsia

This study tests whether combining aspirin with hydroxychloroquine (a drug used for lupus and malaria) can help prevent preeclampsia — a dangerous pregnancy condition involving high blood pressure and organ damage — in women who are at high risk because of their previous pregnancy complications. **You may be eligible if...** - You are a pregnant woman aged 19–50 carrying a single baby - You have at least one prior pregnancy complicated by preeclampsia, fetal growth restriction, or unexplained baby loss (intrauterine fetal death) - You have provided informed consent to participate **You may NOT be eligible if...** - You have been in another interventional clinical trial in the past 3 months - Your baby has been diagnosed with a major abnormality at the 11–13 week scan - You have significant kidney or liver problems - You have a bleeding disorder, peptic ulcer, or allergy to aspirin - You have an allergy to hydroxychloroquine, or known eye disease (hydroxychloroquine can affect vision) Talk to your doctor to see if this trial is right for you.