Low Oxygen Exposure and Weight Status

This study is investigating whether sleeping in a low-oxygen tent at home (similar to conditions at moderate altitude) can help adults with obesity lose more weight when combined with a reduced-calorie diet. Participants will use a specially designed tent for 8 hours each night over 8 weeks, with half assigned to low-oxygen air and half to normal air, alongside a 500-calorie daily reduction. You may be eligible if you are an adult with a BMI between 30 and 39.9, live near Tallahassee, Florida, do not have heart, kidney, or sleep apnea conditions, and are willing to have the tent set up in your home. Participation involves sleeping in the tent nightly, following a reduced-calorie diet, and attending clinic visits for body composition and metabolic measurements. This summary was prepared using AI to help patients understand this research.