RecruitingPhase 3NCT05293080

Early Treatment of Atrial Fibrillation for Stroke Prevention Trial in Acute STROKE

Sponsor

Universitätsklinikum Hamburg-Eppendorf

Enrollment

1,746 participants

Start Date

Nov 6, 2025

Study Type

INTERVENTIONAL

Conditions

Atrial Fibrillation Acute Ischemic Stroke

Summary

This study will determine whether early, comprehensive, rhythm control therapy prevents adverse cardiovascular outcome in patients with acute ischemic stroke and atrial fibrillation compared to usual care.

Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying Medical or interventional therapy for rhythm control in atrial fibrillation (antiarrhythmic drugs, ablation, electric cardio version) and Usual care for atrial fibrillation for people with acute ischemic stroke and atrial fibrillation. The study is currently recruiting participants at 1 location. People eligible for this study include aged 18 Years and older.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

OTHERMedical or interventional therapy for rhythm control in atrial fibrillation (antiarrhythmic drugs, ablation, electric cardio version)

Therapy for early rhythm control will be either by use of approved antiarrhythmic drugs (e.g. amiodarone, dronedarone, flecainide, propafenone), approved approaches and devices for ablation, or electric cardio version.

OTHERUsual care for atrial fibrillation

Usual care for atrial fibrillation according to current guidelines. Usual care will mainly comprise rate control by approved drugs. We expect, that usual care will also comprise therapy for rhythm control in a small group of patients.